Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex.

Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex.

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http://www.wikidata.org/entity/Q36458100
Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingIntermolecular Interactions in a 44 kDa Interferon−Receptor Complex Detected by Asymmetric Reverse-Protonation and Two-Dimensional NOESYObservation of Intermolecular Interactions in Large Protein Complexes by 2D-Double Difference Nuclear Overhauser Enhancement Spectroscopy: Application to the 44 kDa Interferon–Receptor ComplexStructural Linkage between Ligand Discrimination and Receptor Activation by Type I InterferonsStructural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosusGlycoengineering of interferon-β 1a improves its biophysical and pharmacokinetic propertiesImmunosuppressive small molecule discovered by structure-based virtual screening for inhibitors of protein-protein interactions.In silico identification of an interferon inhibitor.IFNA2: The prototypic human alpha interferon.Enhancement of cell type specificity by quantitative modulation of a chimeric ligand.NMR mapping of the IFNAR1-EC binding site on IFNalpha2 reveals allosteric changes in the IFNAR2-EC binding site.Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab.The EM structure of a type I interferon-receptor complex reveals a novel mechanism for cytokine signaling.Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice.Structure determination of a protein assembly by amino acid selective cross-saturation.
P2860

Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex.

Item
http://www.wikidata.org/entity/Q36458100
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Determination of the human typ ...... MR-based model of the complex.
@ast
Determination of the human typ ...... MR-based model of the complex.
@en
type
label
Determination of the human typ ...... MR-based model of the complex.
@ast
Determination of the human typ ...... MR-based model of the complex.
@en
prefLabel
Determination of the human typ ...... MR-based model of the complex.
@ast
Determination of the human typ ...... MR-based model of the complex.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Determination of the human typ ...... MR-based model of the complex.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932