Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity
about
Structure of variant 2 scorpion toxin from Centruroides sculpturatus EwingSolution structure of crotamine, a Na+ channel affecting toxin from Crotalus durissus terrificus venomScorpion toxins specific for Na+-channelsModular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels.Arthropod venoms: a vast arsenal of insecticidal neuropeptides.Isolation of delta-missulenatoxin-Mb1a, the major vertebrate-active spider delta-toxin from the venom of Missulena bradleyi (Actinopodidae).Voltage-gated sodium channel modulation by scorpion alpha-toxins.Solution structure of kurtoxin: a gating modifier selective for Cav3 voltage-gated Ca(2+) channelsComputational methods of studying the binding of toxins from venomous animals to biological ion channels: theory and applications.Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins.Synthesis, solution structure, and phylum selectivity of a spider delta-toxin that slows inactivation of specific voltage-gated sodium channel subtypes.Molecular basis of the high insecticidal potency of scorpion alpha-toxins.Molecular analysis of the sea anemone toxin Av3 reveals selectivity to insects and demonstrates the heterogeneity of receptor site-3 on voltage-gated Na+ channels.First chemical synthesis of a scorpion alpha-toxin affecting sodium channels: the Aah I toxin of Androctonus australis hector.A chimeric scorpion alpha-toxin displays de novo electrophysiological properties similar to those of alpha-like toxins.The specificity of Av3 sea anemone toxin for arthropods is determined at linker DI/SS2-S6 in the pore module of target sodium channels.Isolation and pharmacological characterisation of delta-atracotoxin-Hv1b, a vertebrate-selective sodium channel toxin.The unique pharmacology of the scorpion alpha-like toxin Lqh3 is associated with its flexible C-tail.Delta-atracotoxins from Australian funnel-web spiders compete with scorpion alpha-toxin binding on both rat brain and insect sodium channels.delta-Atracotoxins from australian funnel-web spiders compete with scorpion alpha-toxin binding but differentially modulate alkaloid toxin activation of voltage-gated sodium channels.Characterization of scorpion alpha-like toxin group using two new toxins from the scorpion Leiurus quinquestriatus hebraeus.Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider delta-atracotoxin.Importance of the conserved aromatic residues in the scorpion alpha-like toxin BmK M1: the hydrophobic surface region revisited.
P2860
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P2860
Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Solution structures of a highl ...... mutant with increased activity
@ast
Solution structures of a highl ...... mutant with increased activity
@en
Solution structures of a highl ...... mutant with increased activity
@nl
type
label
Solution structures of a highl ...... mutant with increased activity
@ast
Solution structures of a highl ...... mutant with increased activity
@en
Solution structures of a highl ...... mutant with increased activity
@nl
prefLabel
Solution structures of a highl ...... mutant with increased activity
@ast
Solution structures of a highl ...... mutant with increased activity
@en
Solution structures of a highl ...... mutant with increased activity
@nl
P2093
P356
P1433
P1476
Solution structures of a highl ...... mutant with increased activity
@en
P2093
I Kustanovich
J Anglister
M Gurevitz
N Zilberberg
V Tugarinov
P304
P356
10.1021/BI961497L
P407
P577
1997-03-04T00:00:00Z