Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins. - Wikidata - wikimedia - TriplyDB

Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins.

Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins.

http://www.wikidata.org/entity/Q37344014

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Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor Evolutionary Diversification of Mesobuthus -Scorpion Toxins Affecting Sodium Channels Modular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels.Scorpion venom components that affect ion-channels function Direct evidence that scorpion α-toxins (site-3) modulate sodium channel inactivation by hindrance of voltage-sensor movements Common molecular determinants of tarantula huwentoxin-IV inhibition of Na+ channel voltage sensors in domains II and IV Elucidation of the molecular basis of selective recognition uncovers the interaction site for the core domain of scorpion alpha-toxins on sodium channels.Solution structure of kurtoxin: a gating modifier selective for Cav3 voltage-gated Ca(2+) channels Target-Driven Evolution of Scorpion Toxins Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana.Computational methods of studying the binding of toxins from venomous animals to biological ion channels: theory and applications.Characterization of a novel BmαTX47 toxin modulating sodium channels: the crucial role of expression vectors in toxin pharmacological activity.Finding new cures for neurological disorders: a possible fringe benefit of biodefense research?Wheat germ in vitro translation to produce one of the most toxic sodium channel specific toxins.Design of sodium channel ligands with defined selectivity - a case study in scorpion alpha-toxins.Target-Driven Positive Selection at Hot Spots of Scorpion Toxins Uncovers Their Potential in Design of Insecticides.

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Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins.

http://www.wikidata.org/entity/Q37344014

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 09 June 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Molecular requirements for rec ...... nels by scorpion alpha-toxins.

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Molecular requirements for rec ...... nels by scorpion alpha-toxins.

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Molecular requirements for rec ...... nels by scorpion alpha-toxins.

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Molecular requirements for rec ...... nels by scorpion alpha-toxins.

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prefLabel

Molecular requirements for rec ...... nels by scorpion alpha-toxins.

@en

Molecular requirements for rec ...... nels by scorpion alpha-toxins.

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JBC.M109.021303

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Journal of Biological Chemistry

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Molecular requirements for rec ...... nels by scorpion alpha-toxins.

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Dalia Gordon

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Izhar Karbat

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Lior Cohen

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Michael Gurevitz

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Nitza Ilan

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Roy Kahn

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Stanislav Sokolov

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William A Catterall

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P2860

Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel

Crystal structure of toxin II from the scorpion Androctonus australis Hector refined at 1.3 A resolution

Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

Comparative distribution of voltage-gated sodium channel proteins in human brain

Pathomechanisms in channelopathies of skeletal muscle and brain

Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels.

Orthorhombic crystals and three-dimensional structure of the potent toxin II from the scorpion Androctonus australis Hector.

Diversity of mammalian voltage-gated sodium channels.

Voltage-gated ion channels and hereditary disease.

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20684-20691

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scholarly article

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10.1074/JBC.M109.021303

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31

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284

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2009-06-09T00:00:00Z

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26278865

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19509294

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2742833

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