X-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor binding
about
Defining and designing polymers and hydrogels for neural tissue engineeringStructures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactionsThe Structure of the Glial Cell Line-derived Neurotrophic Factor-Coreceptor Complex: INSIGHTS INTO RET SIGNALING AND HEPARIN BINDINGCharacterization of the Structural Features and Interactions of Sclerostin: MOLECULAR INSIGHT INTO A KEY REGULATOR OF Wnt-MEDIATED BONE FORMATIONComparison of GFL–GFRα complexes: further evidence relating GFL bend angle to RET signallingZebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitroHuman-protein-derived peptides for intracellular delivery of biomolecules.GDNF - a stranger in the TGF-beta superfamily?Ret-dependent and Ret-independent mechanisms of Gfl-induced sensitizationMolecular recognition in bone morphogenetic protein (BMP)/receptor interaction.Neurotrophic factors and their effects in the treatment of multiple sclerosis.The importance of neuronal growth factors in the ovary.Biopharmaceutical Informatics: supporting biologic drug development via molecular modelling and informatics.Glial cell line-derived neurotrophic factor: characterization of mammalian posttranslational modifications.Glial cell line-derived neurotrophic factor family ligands enhance capsaicin-stimulated release of calcitonin gene-related peptide from sensory neurons.Alginate-matrigel microencapsulated schwann cells for inducible secretion of glial cell line derived neurotrophic factor.Investigating the Role of Artemin Glycosylation.Disruption of the GDNF binding site in NCAM dissociates ligand binding and homophilic cell adhesion.The major determinant of the heparin binding of glial cell-line-derived neurotrophic factor is near the N-terminus and is dispensable for receptor binding.Quantitative analysis of the activation mechanism of the multicomponent growth-factor receptor Ret.The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation.Identification of the key amino acids of glial cell line-derived neurotrophic factor family receptor alpha1 involved in its biological function.Identification of a surface for binding to the GDNF-GFR alpha 1 complex in the first cadherin-like domain of RET.Hirschsprung associated GDNF mutations do not prevent RET activation.Effect of the intermolecular disulfide bond on the conformation and stability of glial cell line-derived neurotrophic factor.Functional mapping of receptor specificity domains of glial cell line-derived neurotrophic factor (GDNF) family ligands and production of GFRalpha1 RET-specific agonists.Hirschsprung's disease genes and the development of the enteric nervous system.Structure and biophysical characterisation of the human full-length Neurturin-GFRa2 complex - a role for heparan sulfate in signalling.
P2860
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P2860
X-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor binding
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
X-ray structure of glial cell- ...... lications for receptor binding
@ast
X-ray structure of glial cell- ...... lications for receptor binding
@en
X-ray structure of glial cell- ...... lications for receptor binding
@nl
type
label
X-ray structure of glial cell- ...... lications for receptor binding
@ast
X-ray structure of glial cell- ...... lications for receptor binding
@en
X-ray structure of glial cell- ...... lications for receptor binding
@nl
prefLabel
X-ray structure of glial cell- ...... lications for receptor binding
@ast
X-ray structure of glial cell- ...... lications for receptor binding
@en
X-ray structure of glial cell- ...... lications for receptor binding
@nl
P2860
P356
P1476
X-ray structure of glial cell- ...... lications for receptor binding
@en
P2093
P2860
P356
10.1038/NSB0697-435
P577
1997-06-01T00:00:00Z