The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation.
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The Structure of the Glial Cell Line-derived Neurotrophic Factor-Coreceptor Complex: INSIGHTS INTO RET SIGNALING AND HEPARIN BINDINGComparison of GFL–GFRα complexes: further evidence relating GFL bend angle to RET signallingRET PLCγ phosphotyrosine binding domain regulates Ca2+ signaling and neocortical neuronal migration.Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and arteminGas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling.Solution structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1.Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression.Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases.New targets for glycosaminoglycans and glycosaminoglycans as novel targets.alpha-Helical domains promote translocation of intrinsically disordered polypeptides into the endoplasmic reticulumSpecificity in the crosstalk of TGFbeta/GDNF family members is determined by distinct GFR alpha receptors.Disruption of the GDNF binding site in NCAM dissociates ligand binding and homophilic cell adhesion.The major determinant of the heparin binding of glial cell-line-derived neurotrophic factor is near the N-terminus and is dispensable for receptor binding.The mouse soluble GFRalpha4 receptor activates RET independently of its ligand persephin.Inducible dimerization of RET reveals a specific AKT deregulation in oncogenic signaling.The first cysteine-rich domain of the receptor GFRalpha1 stabilizes the binding of GDNFNon-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.RET dimerizesBinding of EphrinA5 to RET receptor tyrosine kinase: An in vitro study.Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer.Small-Molecule Ligands as Potential GDNF Family Receptor Agonists.Molecular Dynamics Simulations of the Interactions between Glial Cell Line-Derived Neurotrophic Factor Family Receptor GFRα1 and Small-Molecule Ligands
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P2860
The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation.
description
2004 nî lūn-bûn
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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name
The structure of GFRalpha1 dom ...... NF binding and RET activation.
@en
type
label
The structure of GFRalpha1 dom ...... NF binding and RET activation.
@en
prefLabel
The structure of GFRalpha1 dom ...... NF binding and RET activation.
@en
P2093
P2860
P356
P1433
P1476
The structure of GFRalpha1 dom ...... NF binding and RET activation.
@en
P2093
Adrian Goldman
Mart Saarma
Pia Runeberg-Roos
Ulo Puurand
Veli-Matti Leppänen
P2860
P304
P356
10.1038/SJ.EMBOJ.7600174
P407
P577
2004-03-25T00:00:00Z