The 2.0-A resolution crystal structure of a trimeric antibody fragment with noncognate VH-VL domain pairs shows a rearrangement of VH CDR3
about
3D domain swapping: as domains continue to swapDesign of three-dimensional domain-swapped dimers and fibrous oligomersCytochrome c polymerization by successive domain swapping at the C-terminal helixThe crystal structure of a 3D domain-swapped dimer of RNase A at a 2.1-A resolutionTrimeric domain-swapped barnaseScFv multimers of the anti-neuraminidase antibody NC10: shortening of the linker in single-chain Fv fragment assembled in V(L) to V(H) orientation drives the formation of dimers, trimers, tetramers and higher molecular mass multimers.scFv-based fluorogen activating proteins and variable domain inhibitors as fluorescent biosensor platforms.Beyond natural antibodies: the power of in vitro display technologies.Di-, tri- and tetrameric single chain Fv antibody fragments against human CD19: effect of valency on cell binding.Highly enhanced cytotoxicity of a dimeric bispecific diabody, the hEx3 tetrabody.Cytotoxic enhancement of a bispecific diabody by format conversion to tandem single-chain variable fragment (taFv): the case of the hEx3 diabody.Aggregation of γ-crystallins associated with human cataracts via domain swapping at the C-terminal β-strands.A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells.Computer-aided antibody design.Impact of antibody framework residue VH-71 on the stability of a humanised anti-MUC1 scFv and derived immunoenzyme.Anti-EGFR scFv tetramer (tetrabody) with a stable monodisperse structure, strong anticancer effect, and a long in vivo half-lifeX-ray structure analysis of a designed oligomeric miniprotein reveals a discrete quaternary architecture.Multimerization of anti-(epidermal growth factor receptor) IgG fragments induces an antitumor effect: the case for humanized 528 scFv multimers.Antigen binding and stability properties of non-covalently linked anti-CD22 single-chain Fv dimers.Construction of non-covalent single-chain Fv dimers for hepatocellular carcinoma and their biological functions.Noncovalent scFv multimers of tumor-targeting anti-Lewis(y) hu3S193 humanized antibody.Predicting antibody complementarity determining region structures without classification.Modulating Antibody Structure and Function through Directed Mutations and Chemical Rescue.
P2860
Q24644990-B13EF988-4286-4A27-9BDC-026276139327Q27629444-72BA8A3E-21C1-4452-A441-D9139EC94DBBQ27663285-6E873310-7471-44C5-B3C8-6A026D191D55Q27748984-E128D7B9-C831-4C8F-9169-02F59188F187Q27766846-7B6C6F02-60B5-4DAB-8E11-FC0BEAF12D7CQ31805383-FF429747-8A9E-4E88-A45E-E81EA2C4D29FQ33482885-8314991D-1DFB-452C-9B15-391735CE8FD1Q33841864-731A6B35-9549-4FA0-A07F-2A4B1A580DCFQ33867792-C64A1EFC-EC26-4867-9408-3F8F41AF336DQ33966998-041C16B8-B462-4613-ADD6-132724AE9EA4Q34503084-B893B775-6806-474B-8635-81CE8C800D7FQ35081669-C20D0F8B-823E-4815-AD98-C123FE860FB0Q36213205-35C00A35-9389-4E42-A923-677295B3D7A8Q36254449-0D5156F8-D777-49D0-8491-7887C4F2FBEEQ36695056-01755ECF-6A29-4D10-AB15-A08F1661DCADQ36953914-36C985EF-907C-4E90-A581-42BED372BD4FQ37484542-CBF63A0D-74FF-4857-84A7-4CF9AFCEDE22Q39119871-7EF48202-C000-47BA-8276-85003A7AF705Q40482466-004A3193-501A-4487-9651-62A58B34C963Q41140176-8D771F8D-3453-4DB4-8FA7-782457235B71Q42211373-3B076F85-1CF7-456C-A18F-CAB6A22ABE9EQ51514706-C1BC814E-156B-4983-887E-A925D0123A87Q52690535-FAF09D6C-F5A0-44AC-AE3D-E6089A83C219
P2860
The 2.0-A resolution crystal structure of a trimeric antibody fragment with noncognate VH-VL domain pairs shows a rearrangement of VH CDR3
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@ast
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@en
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@nl
type
label
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@ast
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@en
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@nl
prefLabel
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@ast
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@en
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@nl
P2860
P3181
P356
P1476
The 2.0-A resolution crystal s ...... ows a rearrangement of VH CDR3
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.94.18.9637
P407
P577
1997-09-01T00:00:00Z