Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding
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Dehydration of ribonucleotides catalyzed by ribonucleotide reductase: the role of the enzyme.Turning on ribonucleotide reductase by light-initiated amino acid radical generationDynamic dissociating homo-oligomers and the control of protein functionStructural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerizationSite-Specific Incorporation of 3-Nitrotyrosine as a Probe of p K a Perturbation of Redox-Active Tyrosines in Ribonucleotide ReductaseEvaluating the Therapeutic Potential of a Non-Natural Nucleotide That Inhibits Human Ribonucleotide ReductaseStructural interconversions modulate activity of Escherichia coli ribonucleotide reductaseRole of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide ReductaseTangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductaseA new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductaseInhibition of yeast ribonucleotide reductase by Sml1 depends on the allosteric state of the enzyme.Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulationRibonucleotide reductase modularity: Atypical duplication of the ATP-cone domain in Pseudomonas aeruginosaEnzymatically active mammalian ribonucleotide reductase exists primarily as an alpha6beta2 octamerThe origin and evolution of ribonucleotide reductionX-ray Scattering Studies of Protein Structural Dynamics.Allosteric control of three B12-dependent (class II) ribonucleotide reductases. Implications for the evolution of ribonucleotide reduction.Ribonucleotide reduction in Pseudomonas species: simultaneous presence of active enzymes from different classesAdenine recognition: a motif present in ATP-, CoA-, NAD-, NADP-, and FAD-dependent proteins.The conserved Lys-95 charged residue cluster is critical for the homodimerization and enzyme activity of human ribonucleotide reductase small subunit M2Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase.Localization and characterization of two nucleotide-binding sites on the anaerobic ribonucleotide reductase from bacteriophage T4.Mechanism-based inhibition of ribonucleotide reductases: new mechanistic considerations and promising biological applications.B12-dependent ribonucleotide reductases from deeply rooted eubacteria are structurally related to the aerobic enzyme from Escherichia coli.The structural basis for the allosteric regulation of ribonucleotide reductase.Two self-splicing group I introns in the ribonucleotide reductase large subunit gene of Staphylococcus aureus phage Twort.Subunit and small-molecule interaction of ribonucleotide reductases via surface plasmon resonance biosensor analysesThe structural basis of ATP as an allosteric modulatorOligopeptide inhibition of class I ribonucleotide reductases.Proton-coupled electron flow in protein redox machinesStructures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly.Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools.Photo-ribonucleotide reductase β2 by selective cysteine labeling with a radical phototrigger.The Crystal Structure of Thermotoga maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active SiteDirect observation of a transient tyrosine radical competent for initiating turnover in a photochemical ribonucleotide reductase.Insertion of a homing endonuclease creates a genes-in-pieces ribonucleotide reductase that retains function.Direct Interfacial Y731 Oxidation in α2 by a Photoβ2 Subunit of E. coli Class Ia Ribonucleotide Reductase.Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1Re(bpy)(CO)3CN as a probe of conformational flexibility in a photochemical ribonucleotide reductase.Spectroscopic and theoretical approaches for studying radical reactions in class I ribonucleotide reductase.
P2860
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P2860
Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Binding of allosteric effector ...... nes promotes substrate binding
@ast
Binding of allosteric effector ...... nes promotes substrate binding
@en
Binding of allosteric effector ...... nes promotes substrate binding
@nl
type
label
Binding of allosteric effector ...... nes promotes substrate binding
@ast
Binding of allosteric effector ...... nes promotes substrate binding
@en
Binding of allosteric effector ...... nes promotes substrate binding
@nl
prefLabel
Binding of allosteric effector ...... nes promotes substrate binding
@ast
Binding of allosteric effector ...... nes promotes substrate binding
@en
Binding of allosteric effector ...... nes promotes substrate binding
@nl
P2093
P1433
P1476
Binding of allosteric effector ...... nes promotes substrate binding
@en
P2093
P304
P356
10.1016/S0969-2126(97)00259-1
P577
1997-08-15T00:00:00Z