Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
about
Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residueThe 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual featuresThe structure of PhaZ7 at atomic (1.2 Å) resolution reveals details of the active site and suggests a substrate-binding modeCrystal structure of a complex of human chymase with its benzimidazole derived inhibitorSheep mast-cell proteinases-1 and -3: cDNA cloning, primary structure and molecular modelling of the enzymes and further studies on substrate specificityMolecular modeling study for inhibition mechanism of human chymase and its application in inhibitor designCharacterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificityNew, sensitive fluorogenic substrates for human cathepsin G based on the sequence of serpin-reactive site loops.Albumin is a substrate of human chymase. Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site.The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profile.Structural and energetic determinants of the S1-site specificity in serine proteases.Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2' of substrates.A Pulmonary Perspective on GASPIDs: Granule-Associated Serine Peptidases of Immune Defense.Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates.Experimental Arthritis Is Dependent on Mouse Mast Cell Protease-5.A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
P2860
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P2860
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@ast
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@en
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@nl
type
label
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@ast
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@en
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@nl
prefLabel
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@ast
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@en
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@nl
P2093
P356
P1433
P1476
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A
@en
P2093
B F Schmidt
M E McGrath
T Mirzadegan
P304
P356
10.1021/BI971403N
P407
P577
1997-11-25T00:00:00Z