about
Role of somatic cells on dairy processes and products: a reviewThe lysosome: from waste bag to potential therapeutic targetCrystal structure of a putative aspartic proteinase domain of theMycobacterium tuberculosiscell surface antigen PE_PGRS16Analysis of crystal structures of aspartic proteinases: on the role of amino acid residues adjacent to the catalytic site of pepsin-like enzymesThe role of dynamic conformational ensembles in biomolecular recognitionMinimal ensembles of side chain conformers for modeling protein-protein interactionsLeSBT1, a subtilase from tomato plants. Overexpression in insect cells, purification, and characterization.Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations.Folding funnels, binding funnels, and protein functionFolding funnels and binding mechanisms.Knock-down of cathepsin D affects the retinal pigment epithelium, impairs swim-bladder ontogenesis and causes premature death in zebrafish.Partial venom gland transcriptome of a Drosophila parasitoid wasp, Leptopilina heterotoma, reveals novel and shared bioactive profiles with stinging Hymenoptera.Mechanism of substrate recognition by drug-resistant human immunodeficiency virus type 1 protease variants revealed by a novel structural intermediateCathepsin D deficiency is associated with a human neurodegenerative disorder.Cathepsin D primes caspase-8 activation by multiple intra-chain proteolysis.Incorporation of histone derived recombinant protein for enhanced disassembly of core-membrane structured liposomal nanoparticles for efficient siRNA delivery.Molecular dynamics simulations of Factor Xa: insight into conformational transition of its binding subsites.Electrostatic analysis of the hepatitis C virus NS3 helicase reveals both active and allosteric site locations.Alteration of epithelial cell lysosomal integrity induced by bacterial cholesterol-dependent cytolysinsComputational medicinal chemistry in fragment-based drug discovery: what, how and when.The pepsin residue glycine-76 contributes to active-site loop flexibility and participates in catalysisOxidation of protein-bound methionine in Photofrin-photodynamic therapy-treated human tumor cells explored by methionine-containing peptide enrichment and quantitative proteomics approach.Electrostatic switches that mediate the pH-dependent conformational change of "short" recombinant human pseudocathepsin D.Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis.Hybrid 2D/3D-quantitative structure-activity relationship and modeling studies perspectives of pepstatin A analogs as cathepsin D inhibitors.Interactions of a low molecular weight inhibitor from Streptomyces sp. MBR04 with human cathepsin D: implications in mechanism of inactivation.Identification of an IgG CDR sequence contributing to co-purification of the host cell protease cathepsin D.Proton-Coupled Conformational Allostery Modulates the Inhibitor Selectivity for β-Secretase.Conformational dynamics of cathepsin D and binding to a small-molecule BACE1 inhibitor.Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.Molecular Dynamics Simulations of Ligand-Induced Flap Conformational Changes in Cathepsin-D-A Comparative Study.Crystal structure of the retroviral protease-like domain of a protozoal DNA damage-inducible 1 protein
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Conformational switching in an aspartic proteinase
@ast
Conformational switching in an aspartic proteinase
@en
Conformational switching in an aspartic proteinase
@nl
type
label
Conformational switching in an aspartic proteinase
@ast
Conformational switching in an aspartic proteinase
@en
Conformational switching in an aspartic proteinase
@nl
prefLabel
Conformational switching in an aspartic proteinase
@ast
Conformational switching in an aspartic proteinase
@en
Conformational switching in an aspartic proteinase
@nl
P2093
P2860
P356
P1476
Conformational switching in an aspartic proteinase
@en
P2093
P2860
P304
P356
10.1038/2306
P407
P577
1998-10-01T00:00:00Z