NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions
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The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnoverThe Vpr protein from HIV-1: distinct roles along the viral life cycleThe HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition poreHuman immunodeficiency virus type 1 Vpr-mediated G(2) cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2AControl of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiaeNMR structure of the (1-51) N-terminal domain of the HIV-1 regulatory protein VprSolution structure of human immunodeficiency virus type 1 Vpr(13-33) peptide in micellesStructure of human immunodeficiency virus type 1 Vpr(34-51) peptide in micelle containing aqueous solutionThe C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathwayRoles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactionsAnti-cancer effect of HIV-1 viral protein R on doxorubicin resistant neuroblastomaFunctional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest.The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, R90Evidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr SequencesFunctional role of residues corresponding to helical domain II (amino acids 35 to 46) of human immunodeficiency virus type 1 Vpr.Vpr-host interactions during HIV-1 viral life cycle.Functional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.New EMBO members' review: viral and bacterial proteins regulating apoptosis at the mitochondrial levelDocking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction.Mitochondria: a target for cancer therapy.Vpr cytopathicity independent of G2/M cell cycle arrest in human immunodeficiency virus type 1-infected CD4+ T cellsHIV-1 Vpr: mechanisms of G2 arrest and apoptosis.Viral factors in non-progression.The HIV-derived protein Vpr52-96 has anti-glioma activity in vitro and in vivo.HIV-1 Vpr-a still "enigmatic multitasker".Roles of Vpr and Vpx in modulating the virus-host cell relationship.Delineating HIV-associated neurocognitive disorders using transgenic models: the neuropathogenic actions of Vpr.Defining the roles for Vpr in HIV-1-associated neuropathogenesis.Human Immunodeficiency Virus Promotes Mitochondrial Toxicity.Transdominant activity of human immunodeficiency virus type 1 Vpr with a mutation at residue R73.Efficient DNA transfection mediated by the C-terminal domain of human immunodeficiency virus type 1 viral protein RTwo putative alpha-helical domains of human immunodeficiency virus type 1 Vpr mediate nuclear localization by at least two mechanisms.Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G(2) cell cycle arrestBiochemical analyses of the interactions between human immunodeficiency virus type 1 Vpr and p6(Gag).Simultaneous positive and purifying selection on overlapping reading frames of the tat and vpr genes of simian immunodeficiency virus.Mitochondrial dysfunction in lyssavirus-induced apoptosis.HIV-1 Vpr-induced cell death in Schizosaccharomyces pombe is reminiscent of apoptosis.Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin.
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P2860
NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
NMR structure of the (52-96) C ...... into its biological functions
@ast
NMR structure of the (52-96) C ...... into its biological functions
@en
NMR structure of the (52-96) C ...... into its biological functions
@nl
type
label
NMR structure of the (52-96) C ...... into its biological functions
@ast
NMR structure of the (52-96) C ...... into its biological functions
@en
NMR structure of the (52-96) C ...... into its biological functions
@nl
prefLabel
NMR structure of the (52-96) C ...... into its biological functions
@ast
NMR structure of the (52-96) C ...... into its biological functions
@en
NMR structure of the (52-96) C ...... into its biological functions
@nl
P2093
P3181
P356
P1476
NMR structure of the (52-96) C ...... into its biological functions
@en
P2093
P304
P3181
P356
10.1006/JMBI.1998.2381
P407
P577
1999-02-05T00:00:00Z