Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin.
about
HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction.Inhibition of NF-κB activity by HIV-1 Vpr is dependent on Vpr binding protein.The human immunodeficiency virus type 1 Vpr protein and its carboxy-terminally truncated form induce apoptosis in tumor cells.The HIV-derived protein Vpr52-96 has anti-glioma activity in vitro and in vivo.Viral protein R of HIV type-1 induces retrotransposition and upregulates glutamate synthesis by the signal transducer and activator of transcription 1 signaling pathway.HIV-1 Vpr deregulates calcium secretion in neural cells.Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response.
P2860
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P2860
Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年學術文章
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name
Molecular mimicry in inducing ...... e anticancer agent, cisplatin.
@en
type
label
Molecular mimicry in inducing ...... e anticancer agent, cisplatin.
@en
prefLabel
Molecular mimicry in inducing ...... e anticancer agent, cisplatin.
@en
P2093
P2860
P356
P1433
P1476
Molecular mimicry in inducing ...... he anticancer agent, cisplatin
@en
P2093
A Srinivasan
B E Sawaya
B P Roques
C B Pattillo
K Siddiqui
K Urbanska
P2860
P2888
P356
10.1038/SJ.ONC.1210632
P407
P577
2007-07-23T00:00:00Z
P5875
P6179
1029171824