about
The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of SrcThe conservation pattern of short linear motifs is highly correlated with the function of interacting protein domainsDisruption of Fyn SH3 domain interaction with a proline-rich motif in liver kinase B1 results in activation of AMP-activated protein kinaseSRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactomeShort Linear Motifs recognized by SH2, SH3 and Ser/Thr Kinase domains are conserved in disordered protein regionsRecruitment and activation of SHP-1 protein-tyrosine phosphatase by human platelet endothelial cell adhesion molecule-1 (PECAM-1). Identification of immunoreceptor tyrosine-based inhibitory motif-like binding motifs and substratesFyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinaseSHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activationTyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of LckIdentification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptorFYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cellsFibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein CrkMelusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domainA phosphotyrosine displacement mechanism for activation of Src by PTPalphaA natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisA phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cellsAlternative modes of binding of proteins with tandem SH2 domainsClass II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptorsAssociation of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signalingSik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding abilityAFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomesThe interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cellsStructural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein)Direct identification of a major autophosphorylation site on vascular endothelial growth factor receptor Flt-1 that mediates phosphatidylinositol 3'-kinase bindingTYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1BA "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndromeA novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signalingUse of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasisMitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylationA quantitative protein interaction network for the ErbB receptors using protein microarraysEnhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactomeTyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkLPhosphorylated alpha-actinin and protein-tyrosine phosphatase 1B coregulate the disassembly of the focal adhesion kinase x Src complex and promote cell migrationThe Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGFStructural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domainIdentification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activationMetastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancerThe elucidation of novel SH2 binding sites on PLD2Csk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancer
P2860
Q21092219-D73E0532-30E9-4059-931E-CA3AB3B540FFQ21093356-8443F2E9-4AEB-4710-A3EB-5CE8AF0CB770Q21132307-947849FA-26AF-4D81-8751-373EEFAA8C09Q21245515-836F5FBD-7F67-4B7A-8AA8-9856C80DEE54Q21263144-F007703E-58EE-4491-B78B-0ABA9B3CD67DQ22003966-0CAEBF72-40D3-4B7A-9A1A-CAFC23725D37Q22008672-3A368086-D690-4C22-8D76-2B3506B01AFEQ22009430-CEC94A66-EBBC-4525-973F-2BB60F8C2D3DQ22009540-DBEA699D-561D-4BA6-B0DB-EFA4DB30C28DQ22010151-20E7DDC8-615F-4AF8-80CD-A33737B0E4D6Q22010396-BBFD97F5-80CC-482E-A5A6-B8517E20BFE5Q22010490-3E24CCFC-9FEA-49C8-950C-BD66AC90D8D8Q22010596-724B8D7A-E299-4077-8544-8828E1A2E434Q22253266-C20AA61C-91E7-4487-8A9E-1EEE2F1B6D60Q22253346-97A12383-A0DE-40C7-8BAE-4E7A00E365FCQ22253428-DDBC1176-0E2D-4142-BCC9-9641DB6E8069Q22253843-0D8998B1-7938-4E0B-AF9E-698061B64F84Q22254063-90553281-1419-4754-B18C-E9589CC5F4A4Q22254087-B936F18E-88CA-4DB4-89F8-9FA90BB0A6ACQ22254678-A8543751-262D-435E-B7C6-14F9F600031CQ23910475-0B084EEC-BFB9-4E6B-8A97-F7B3567FEF00Q24291061-B5F38749-48DC-4D43-8DE6-DE208CA86079Q24291278-3043E498-9237-4878-853A-ACF770B34695Q24291394-B44A5A7D-02E6-4323-A3C9-5805B72A1599Q24291582-FCE4A71D-90CA-4C8E-B742-31564F82415CQ24291860-09988157-3FA2-4F8E-87E5-70EC6E4714E4Q24292245-FE8C4F47-A83E-4057-91D2-CDC934839571Q24292458-87FBA416-52C5-4030-8FE5-52DEAF24AAD2Q24292477-444094D7-7900-4379-8373-665BE9CDE4A1Q24292854-C310E5B0-A9C0-46AD-8D19-4B9742963FB0Q24293746-CCD5913C-AD10-4960-B2AD-A351388CB7CAQ24294625-79901C98-ADD1-4BA8-A166-C086F1CFEB56Q24295091-AB4F112C-6B21-4630-A9D3-8232307D967EQ24295196-93110388-6272-471E-AADA-4C8349FE7296Q24295239-C644FB6E-44CF-4A83-89CF-E7C815E22AB6Q24297924-24C3CEA8-54AE-4309-B661-590F5BC913C7Q24299920-FBA57208-E7E6-4754-AA24-E063F3920254Q24300187-B92E68C4-DA09-4F42-9286-DF7F637ACB76Q24300871-C23F27EB-4B61-40B8-87E6-24921DE11014Q24301665-E86131FB-B4B7-4835-9FBC-64A254DF6BE9
P2860
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
SH2 domains recognize specific phosphopeptide sequences
@ast
SH2 domains recognize specific phosphopeptide sequences
@en
SH2 domains recognize specific phosphopeptide sequences
@nl
type
label
SH2 domains recognize specific phosphopeptide sequences
@ast
SH2 domains recognize specific phosphopeptide sequences
@en
SH2 domains recognize specific phosphopeptide sequences
@nl
prefLabel
SH2 domains recognize specific phosphopeptide sequences
@ast
SH2 domains recognize specific phosphopeptide sequences
@en
SH2 domains recognize specific phosphopeptide sequences
@nl
P2093
P3181
P1433
P1476
SH2 domains recognize specific phosphopeptide sequences
@en
P2093
M Chaudhuri
R J Lechleider
S E Shoelson
S Ratnofsky
Z Songyang
P304
P3181
P356
10.1016/0092-8674(93)90404-E
P407
P577
1993-03-12T00:00:00Z