A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis
about
The intracellular domain of ErbB4 induces differentiation of mammary epithelial cellsInteractions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathwaysPhosphorylation of ErbB4 on tyrosine 1056 is critical for ErbB4 coupling to inhibition of colony formation by human mammary cell linesN-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration.Host gene targets for novel influenza therapies elucidated by high-throughput RNA interference screensHuman epidermal growth factor receptor signaling in acute lung injuryProteolytic Processing of ErbB4 in Breast CancerNuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer.Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathwaySystemic analysis of gene expression profiles identifies ErbB3 as a potential drug target in pediatric alveolar rhabdomyosarcomaThe E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradationErbB4 expression in neural progenitor cells (ST14A) is necessary to mediate neuregulin-1beta1-induced migrationCell death or survival promoted by alternative isoforms of ErbB4Tumor suppressor Nf2/merlin drives Schwann cell changes following electromagnetic field exposure through Hippo-dependent mechanisms.Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategyErbB4, a receptor tyrosine kinase, coordinates organization of the seminiferous tubules in the developing testisThe interaction of the ErbB4 intracellular domain p80 with α-enolase in the nuclei is associated with the inhibition of the neuregulin1-dependent cell proliferation.The localization of HER4 intracellular domain and expression of its alternately-spliced isoforms have prognostic significance in ER+ HER2- breast cancer.Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary glandE3 ubiquitin ligases in ErbB receptor quantity control.The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics.The epidermal growth factor receptor family in breast cancer.Ligand stimulation of ErbB4 and a constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines.Amplification of HER-2 in gastric carcinoma: association with Topoisomerase IIalpha gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab.Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility geneCorrelation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia.MAPK pathways in radiation responses.The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.Regulation of neuroblast mitosis is determined by PACAP receptor isoform expressionThe effect of epiregulin on epidermal growth factor receptor expression and proliferation of oral squamous cell carcinoma cell lines.Interaction with ErbB4 promotes hypoxia-inducible factor-1α signaling.ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.Protein inhibitor of activated STAT3 (PIAS3) protein promotes SUMOylation and nuclear sequestration of the intracellular domain of ErbB4 protein.ErbB4 isoforms selectively regulate growth factor induced Madin-Darby canine kidney cell tubulogenesis.Neuregulin-4 is a survival factor for colon epithelial cells both in culture and in vivoA simple and reproducible scoring system for EGFR in colorectal cancer: application to prognosis and prediction of response to preoperative brachytherapy.Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms.Genetic variants in ERBB4 is associated with chronic hepatitis B virus infectionNeurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.Directing HER4 mRNA expression towards the CYT2 isoform by antisense oligonucleotide decreases growth of breast cancer cells in vitro and in vivo.
P2860
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P2860
A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@ast
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@en
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@en-gb
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@nl
type
label
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@ast
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@en
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@en-gb
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@nl
prefLabel
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@ast
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@en
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@en-gb
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@nl
P2093
P2860
P356
P1476
A natural ErbB4 isoform that d ...... but not survival or chemotaxis
@en
P2093
E Santiestevan
M Klagsbrun
M Sundvall
V Kainulainen
P2860
P304
P356
10.1074/JBC.275.12.8641
P407
P577
2000-03-01T00:00:00Z