Glycosylation-induced conformational modification positively regulates receptor-receptor association: a study with an aberrant epidermal growth factor receptor (EGFRvIII/DeltaEGFR) expressed in cancer cells.
about
Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancerThe epidermal growth factor receptor variant III (EGFRvIII): where wild things are alteredGas6-axl receptor signaling is regulated by glucose in vascular smooth muscle cellsEvidence of high incidence of EGFRvIII expression and coexpression with EGFR in human invasive breast cancer by laser capture microdissection and immunohistochemical analysis.The constitutive activity of epidermal growth factor receptor vIII leads to activation and differential trafficking of wild-type epidermal growth factor receptor and erbB2The glycosynapseRegulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerizationThe epidermal growth factor receptor in malignant gliomas: pathogenesis and therapeutic implications.The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor speciesNexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity.N-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes.Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor.A structural perspective on the regulation of the epidermal growth factor receptor.High predictive value of epidermal growth factor receptor phosphorylation but not of EGFRvIII mutation in resected stage I non-small cell lung cancer (NSCLC)Epidermal growth factor, neurotrophins and the metastatic cascade in prostate cancer.Functional consequences of alteration of N-linked glycosylation sites on the neurokinin 1 receptor.Characterization and immunotherapeutic implications for a novel antibody targeting interleukin (IL)-13 receptor α2.EGFRvIII undergoes activation-dependent downregulation mediated by the Cbl proteins.Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains.Synergistic antitumor efficacy against the EGFRvIII+HER2+ breast cancers by combining trastuzumab with anti-EGFRvIII antibody CH12Glioma-specific antigens for immune tumor therapy.Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis.Glycomics and glycoproteomics of membrane proteins and cell-surface receptors: Present trends and future opportunities.Inhibition of N-linked glycosylation disrupts receptor tyrosine kinase signaling in tumor cells.Annotating cancer variants and anti-cancer therapeutics in reactome.Glioma Specific Extracellular Missense Mutations in the First Cysteine Rich Region of Epidermal Growth Factor Receptor (EGFR) Initiate Ligand Independent Activation.The single kinin receptor signals to separate and independent physiological pathways in Malpighian tubules of the yellow fever mosquito.Non-Ligand-Induced Dimerization is Sufficient to Initiate the Signalling and Endocytosis of EGF ReceptorN-Glycans in cancer progression.EGF receptor variant III as a target antigen for tumor immunotherapy.EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy.Glycoproteomics using fluid-based specimens in the discovery of lung cancer protein biomarkers: promise and challenge.Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers.Targeting EGFR resistance networks in head and neck cancer.2-Deoxy-d-glucose Suppresses the In Vivo Antitumor Efficacy of Erlotinib in Head and Neck Squamous Cell Carcinoma Cells.Quantitative proteomic profiling identifies protein correlates to EGFR kinase inhibitionEfficient synthesis of chloro-derivatives of sialosyllactosylceramide, and their enhanced inhibitory effect on epidermal growth factor receptor activation.Application of glycoproteomics for the discovery of biomarkers in lung cancer.Metabolism, cell surface organization, and disease.
P2860
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P2860
Glycosylation-induced conformational modification positively regulates receptor-receptor association: a study with an aberrant epidermal growth factor receptor (EGFRvIII/DeltaEGFR) expressed in cancer cells.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@ast
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@en
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@nl
type
label
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@ast
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@en
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@nl
altLabel
Glycosylation-induced conforma ...... GFR) expressed in cancer cells
@en
prefLabel
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@ast
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@en
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@nl
P2093
P2860
P3181
P356
P1476
Glycosylation-induced conforma ...... FR) expressed in cancer cells.
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M005599200
P407
P577
2001-02-16T00:00:00Z