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Structural alterations of the epidermal growth factor receptor gene in human gliomas

Structural alterations of the epidermal growth factor receptor gene in human gliomas

http://www.wikidata.org/entity/Q36930689

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A quantitative protein interaction network for the ErbB receptors using protein microarrays EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma A census of human cancer genes IDH1 and IDH2 mutations in gliomas PTPmu suppresses glioma cell migration and dispersal Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications Soluble Epidermal Growth Factor Receptors (sEGFRs) in Cancer: Biological Aspects and Clinical Relevance Radioresistance of Brain Tumors Stress Response Leading to Resistance in Glioblastoma-The Need for Innovative Radiotherapy (iRT) Concepts Molecular characterizations of glioblastoma, targeted therapy, and clinical results to date Biomarkers for glioma immunotherapy: the next generation G protein-coupled receptors as oncogenic signals in glioma: emerging therapeutic avenues Current vaccine trials in glioblastoma: a review Vaccine therapies in malignant glioma Deregulated signaling pathways in glioblastoma multiforme: molecular mechanisms and therapeutic targets EGFR Amplification and Glioblastoma Stem-Like Cells Immunotherapy advances for glioblastoma The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered Targeting oncogenic ALK and MET: a promising therapeutic strategy for glioblastoma An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma Transmigration of neural stem cells across the blood brain barrier induced by glioma cells Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer Glycosylation-induced conformational modification positively regulates receptor-receptor association: a study with an aberrant epidermal growth factor receptor (EGFRvIII/DeltaEGFR) expressed in cancer cells.Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain Concepts of immunotherapy for glioma Dendritic Cell-Based Immunotherapy Treatment for Glioblastoma Multiforme The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling Chromosome 7 aneusomy. A marker for metastatic melanoma? Expression of the epidermal growth factor receptor gene and chromosome 7 aneusomy in nevi, primary malignant melanomas and metastases Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway Immunoglobulin genes implicated in glioma risk Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma Specific and sensitive hydrolysis probe-based real-time PCR detection of epidermal growth factor receptor variant III in oral squamous cell carcinoma The mutational landscape of head and neck squamous cell carcinoma ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells.Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter.

P2860

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P2860

Structural alterations of the epidermal growth factor receptor gene in human gliomas

http://www.wikidata.org/entity/Q36930689

description

1992 nî lūn-bûn

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1992年の論文

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1992年論文

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1992年論文

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1992年論文

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1992年論文

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1992年論文

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1992年论文

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1992年论文

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1992年论文

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name

Structural alterations of the epidermal growth factor receptor gene in human gliomas

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Structural alterations of the epidermal growth factor receptor gene in human gliomas

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Structural alterations of the epidermal growth factor receptor gene in human gliomas

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Structural alterations of the epidermal growth factor receptor gene in human gliomas

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P2093

Bigner DS

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Bigner SH

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Grzeschik CH

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Humphrey PA

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Ruppert JM

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Wong AJ

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P2860

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

A simple and very efficient method for generating cDNA libraries

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 mouse fibroblasts.

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.

Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumors.

Differences in sequences encoding the carboxyl-terminal domain of the epidermal growth factor receptor correlate with differences in the disease potential of viral erbB genes.

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.

Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells.

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2965-2969

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7

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Bert Vogelstein

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21599130

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1557402

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48784

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