The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.
about
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learningImprinted Rasgrf1 expression in neonatal mice affects olfactory learning and memoryImprint switch mutations at Rasgrf1 support conflict hypothesis of imprinting and define a growth control mechanism upstream of IGF1Molecular Mechanisms Elicited by d-Aspartate in Leydig Cells and SpermatogoniaThe NMDA receptor complex: a multifunctional machine at the glutamatergic synapseCurrent view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2Recent progress in understanding subtype specific regulation of NMDA receptors by G Protein Coupled Receptors (GPCRs)Activated Ras as a Therapeutic Target: Constraints on Directly Targeting Ras Isoforms and Wild-Type versus Mutated ProteinsReactive Oxygen Species: Physiological and Physiopathological Effects on Synaptic PlasticitySegregation and crosstalk of D1 receptor-mediated activation of ERK in striatal medium spiny neurons upon acute administration of psychostimulantsNMDA and dopamine converge on the NMDA-receptor to induce ERK activation and synaptic depression in mature hippocampusThe effects of NR2 subunit-dependent NMDA receptor kinetics on synaptic transmission and CaMKII activationRequirement for Plk2 in orchestrated ras and rap signaling, homeostatic structural plasticity, and memoryKalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and functionSCLIP, a microtubule-destabilizing factor, interacts with RasGRF1 and inhibits its ability to promote Rac activation and neurite outgrowthDepolarization activates ERK and proline-rich tyrosine kinase 2 (PYK2) independently in different cellular compartments in hippocampal slicesBrain-derived neurotrophic factor regulation of N-methyl-D-aspartate receptor-mediated synaptic currents in suprachiasmatic nucleus neuronsAndrogens activate mitogen-activated protein kinase signaling: role in neuroprotectionNR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticityDevelopmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREBN-methyl-D-aspartic acid receptor activation downregulates expression of δ subunit-containing GABAA receptors in cultured hippocampal neurons.State-dependent Ras signaling and AMPA receptor trafficking.Activation of the neuronal extracellular signal-regulated kinase 2 in the spinal cord dorsal horn is required for complete Freund's adjuvant-induced pain hypersensitivityActivation of extracellular signal-regulated kinase in the anterior cingulate cortex contributes to the induction and expression of affective pain.Estrogen facilitates spinal cord synaptic transmission via membrane-bound estrogen receptors: implications for pain hypersensitivity.The distinct role of NR2B subunit in the enhancement of visual plasticity in adulthood.A quantitative method to assess extrasynaptic NMDA receptor function in the protective effect of synaptic activity against neurotoxicityAge-dependent role for Ras-GRF1 in the late stages of adult neurogenesis in the dentate gyrusDomain contributions to signaling specificity differences between Ras-guanine nucleotide releasing factor (Ras-GRF) 1 and Ras-GRF2Ethanol-withdrawal seizures are controlled by tissue plasminogen activator via modulation of NR2B-containing NMDA receptors.Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatumInhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia.Downregulation of Kv4.2 channels mediated by NR2B-containing NMDA receptors in cultured hippocampal neuronsNMDA receptor- and ERK-dependent histone methylation changes in the lateral amygdala bidirectionally regulate fear memory formation.Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation.The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens.Differential hippocampal gene expression is associated with climate-related natural variation in memory and the hippocampus in food-caching chickadeesNeuroprotective effects of Asiaticoside.Calcium signaling in synapse-to-nucleus communicationSignaling cascades regulating NMDA receptor sensitivity to ethanol.
P2860
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P2860
The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@ast
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@en
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@nl
type
label
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@ast
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@en
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@nl
altLabel
The NMDA receptor is coupled t ...... ction between NR2B and RasGRF1
@en
prefLabel
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@ast
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@en
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@nl
P2093
P50
P3181
P1433
P1476
The NMDA receptor is coupled t ...... tion between NR2B and RasGRF1.
@en
P2093
Anton Ivanov
Grigory Krapivinsky
Luba Krapivinsky
Roman Tyzio
Yehezkel Ben-Ari
Yunona Manasian
P304
P3181
P356
10.1016/S0896-6273(03)00645-7
P407
P577
2003-11-13T00:00:00Z