Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system.
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Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IVCloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramerCloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunitERp60 does not substitute for protein disulphide isomerase as the beta-subunit of prolyl 4-hydroxylaseProlyl 4-hydroxylaseRegulation of type II collagen synthesis during osteoarthritis by prolyl-4-hydroxylases: possible influence of low oxygen levelsCrystal Structure of Prolyl 4-Hydroxylase from Bacillus anthracisType XIII collagen is identified as a plasma membrane proteinSite-directed mutagenesis of human protein disulphide isomerase: effect on the assembly, activity and endoplasmic reticulum retention of human prolyl 4-hydroxylase in Spodoptera frugiperda insect cellsProlyl 4-hydroxylation regulates Argonaute 2 stabilityStringency of the 2-His-1-Asp active-site motif in prolyl 4-hydroxylaseIdentification and characterization of a third human, rat, and mouse collagen prolyl 4-hydroxylase isoenzymeIdentification of a novel proline-rich peptide-binding domain in prolyl 4-hydroxylaseProteomic analysis of iron overload in human hepatoma cells.Determination and comparison of specific activity of the HIF-prolyl hydroxylases.Conformational preferences of substrates for human prolyl 4-hydroxylaseThe collagen V homotrimer [alpha1(V)](3) production is unexpectedly favored over the heterotrimer [alpha1(V)](2)alpha2(V) in recombinant expression systems.Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.Characterization of the human and mouse genes for the alpha subunit of type II prolyl 4-hydroxylase. Identification of a previously unknown alternatively spliced exon and its expression in various tissues.Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity.Specific inhibition of eIF-5A and collagen hydroxylation by a single agent. Antiproliferative and fibrosuppressive effects on smooth muscle cells from human coronary arteries.Expression of a glycosylphosphatidylinositol-anchored Trypanosoma brucei transferrin-binding protein complex in insect cells.Novel roles for protein disulphide isomerase in disease states: a double edged sword?Characterization of a novel third member of the human cytomegalovirus glycoprotein H-glycoprotein L complex.Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.Generating an unfoldase from thioredoxin-like domainsThree binding sites in protein-disulfide isomerase cooperate in collagen prolyl 4-hydroxylase tetramer assembly.A hypodermally expressed prolyl 4-hydroxylase from the filarial nematode Brugia malayi is soluble and active in the absence of protein disulfide isomerase.The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits.Collagenous sequence governs the trimeric assembly of collagen XII.Domains b' and a' of protein disulfide isomerase fulfill the minimum requirement for function as a subunit of prolyl 4-hydroxylase. The N-terminal domains a and b enhances this function and can be substituted in part by those of ERp57.Coexpression of alpha and beta subunits of prolyl 4-hydroxylase stabilizes the triple helix of recombinant human type X collagen.Collagens and their abnormalities in a wide spectrum of diseases.Thioredoxin domain non-equivalence and anti-chaperone activity of protein disulfide isomerase mutants in vivo.Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylaseInvolvement of prolyl 4-hydroxylase in the assembly of trimeric minicollagen XII. Study in a baculovirus expression system.Intracellular dissociation and reassembly of prolyl 4-hydroxylase:the alpha-subunits associated with the immunoglobulin-heavy-chain binding protein (BiP) allowing reassembly with the beta-subunit.Co-expression of the alpha subunit of human prolyl 4-hydroxylase with BiP polypeptide in insect cells leads to the formation of soluble and insoluble complexes. Soluble alpha-subunit-BiP complexes have no prolyl 4-hydroxylase activity.Production of recombinant human type I procollagen trimers using a four-gene expression system in the yeast Saccharomyces cerevisiae.The acidic C-terminal domain of protein disulfide isomerase is not critical for the enzyme subunit function or for the chaperone or disulfide isomerase activities of the polypeptide.
P2860
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P2860
Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system.
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Characterization of the human ...... baculovirus expression system.
@ast
Characterization of the human ...... baculovirus expression system.
@en
Characterization of the human ...... baculovirus expression system.
@nl
type
label
Characterization of the human ...... baculovirus expression system.
@ast
Characterization of the human ...... baculovirus expression system.
@en
Characterization of the human ...... baculovirus expression system.
@nl
altLabel
Characterization of the human ...... baculovirus expression system
@en
prefLabel
Characterization of the human ...... baculovirus expression system.
@ast
Characterization of the human ...... baculovirus expression system.
@en
Characterization of the human ...... baculovirus expression system.
@nl
P2093
P2860
P356
P1476
Characterization of the human ...... baculovirus expression system.
@en
P2093
K I Kivirikko
M Marttila
T Pihlajaniemi
P2860
P304
P356
10.1073/PNAS.89.16.7467
P407
P577
1992-08-15T00:00:00Z