Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityRPA homologs and ssDNA processing during meiotic recombinationATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to AdaptorFunctional Role of NBS1 in Radiation Damage Response and Translesion DNA SynthesisDouble-strand break repair on sex chromosomes: challenges during male meiotic prophaseChemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promisingMechanisms and regulation of mitotic recombination in Saccharomyces cerevisiaeThe Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changesRepair of strand breaks by homologous recombinationInflammation-induced cell proliferation potentiates DNA damage-induced mutations in vivoCOM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joiningDNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease ActivitiesEnd-resection at DNA double-strand breaks in the three domains of lifeCyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection.Noncanonical views of homology-directed DNA repairMicrohomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repairEXD2 promotes homologous recombination by facilitating DNA end resectionBRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous RecombinationConnecting by breaking and repairing: mechanisms of DNA strand exchange in meiotic recombinationThe role of the Mre11-Rad50-Nbs1 complex in double-strand break repair-facts and mythsSae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenanceThe SWI/SNF ATP-dependent nucleosome remodeler promotes resection initiation at a DNA double-strand break in yeast.Pseudosynapsis and decreased stringency of meiotic repair pathway choice on the hemizygous sex chromosome of Caenorhabditis elegans malesEnd resection at double-strand breaks: mechanism and regulation.The meiotic checkpoint network: step-by-step through meiotic prophaseDNA repair: Making the cut.Coincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nucleaseA multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae.Mechanism and regulation of meiotic recombination initiation.Recognition and repair of chemically heterogeneous structures at DNA endsEvidence for distinct functions of MRE11 in Arabidopsis meiosis.Pre-exposure to ionizing radiation stimulates DNA double strand break end resection, promoting the use of homologous recombination repairCrystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination.Functional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break.Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisionsBiochemical mechanism of DSB end resection and its regulation.EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele.DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous Recombination
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P2860
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
@ast
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
@en
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1.
@nl
type
label
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
@ast
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
@en
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1.
@nl
altLabel
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
@en
prefLabel
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
@ast
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
@en
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1.
@nl
P2093
P2860
P3181
P356
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P1476
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
@en
P2093
Matthew J Neale
Sarah E L Phelps
Stephen Gray
Valerie Garcia
P2860
P2888
P3181
P356
10.1038/NATURE10515
P407
P577
2011-10-16T00:00:00Z
P5875
P6179
1040996569