Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway? - Wikidata - wikimedia - TriplyDB

Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

http://www.wikidata.org/entity/Q28083182

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DNA Damage and Pulmonary Hypertension Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer DNA polymerase θ (POLQ), double-strand break repair, and cancer Noncanonical views of homology-directed DNA repair Microhomology-mediated end joining: new players join the team Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins.Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.Microhomology-mediated end joining induces hypermutagenesis at breakpoint junctions.Selective gene dosage by CRISPR-Cas9 genome editing in hexaploid Camelina sativa.Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repair SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression.Do DNA Double-Strand Breaks Drive Aging?Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism The Transcriptional Response to DNA-Double-Strand Breaks in Physcomitrella patens Risky business: Microhomology-mediated end joining.Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences Mechanism and regulation of DNA end resection in eukaryotes When Genome Maintenance Goes Badly Awry.Rapid Screening for CRISPR-Directed Editing of the Drosophila Genome Using white Coconversion.The DNA resection protein CtIP promotes mammary tumorigenesis.Simple and Efficient Targeting of Multiple Genes Through CRISPR-Cas9 in Physcomitrella patens.Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation.Aberrant DNA Double-strand Break Repair Threads in Breast Carcinoma: Orchestrating Genomic Insult Survival.Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination.Stop pulling my strings - what telomeres taught us about the DNA damage response.CtIP/Ctp1/Sae2, molecular form fit for function.Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.Protecting DNA from errors and damage: an overview of DNA repair mechanisms in plants compared to mammals.Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA.The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair.Relocalization of DNA lesions to the nuclear pore complex.Regulation of non-homologous end joining via post-translational modifications of components of the ligation step.The control of DNA repair by the cell cycle.Cell cycle-dependent control of homologous recombination.DNA Instability Maintains the Repeat Length of the Yeast RNA Polymerase II C-terminal Domain.Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes.Dual loss of human POLQ and LIG4 abolishes random integration.Modification of 3' Terminal Ends of DNA and RNA Using DNA Polymerase θ Terminal Transferase Activity.Molecular characterization of cell-free eccDNAs in human plasma.Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development.

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

http://www.wikidata.org/entity/Q28083182

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2015 nî lūn-bûn

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2015 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2015 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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J.TIBS.2015.08.006

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Trends in Biochemical Sciences

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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Lorraine S. Symington

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P2860

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

DNA end-joining catalyzed by human cell-free extracts

POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells

Promiscuous DNA synthesis by human DNA polymerase θ

HARP is an ATP-driven annealing helicase

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

CDK targets Sae2 to control DNA-end resection and homologous recombination

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

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