Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins.
about
Cohen syndrome is caused by mutations in a novel gene, COH1, encoding a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transportSorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35pA conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease.Organization of the yeast Golgi complex into at least four functionally distinct compartments.Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutantSOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals.Retrieval of resident late-Golgi membrane proteins from the prevacuolar compartment of Saccharomyces cerevisiae is dependent on the function of Grd19p.Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteinsVps13F links bacterial recognition and intracellular killing in DictyosteliumAllelic heterogeneity in the COH1 gene explains clinical variability in Cohen syndrome.Brain, blood, and iron: perspectives on the roles of erythrocytes and iron in neurodegeneration.Cohen syndrome-associated protein, COH1, is a novel, giant Golgi matrix protein required for Golgi integrityVacuolar protein sorting protein 13A, TtVPS13A, localizes to the tetrahymena thermophila phagosome membrane and is required for efficient phagocytosisNovel VPS13B Mutations in Three Large Pakistani Cohen Syndrome Families Suggests a Baloch Variant with Autistic-Like Features.Drosophila Vps13 Is Required for Protein Homeostasis in the Brain.The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPase.Direct binding of the Kex2p cytosolic tail to the VHS domain of yeast Gga2p facilitates TGN to prevacuolar compartment transport and is regulated by phosphorylationSuppressor of K+ transport growth defect 1 (SKD1) interacts with RING-type ubiquitin ligase and sucrose non-fermenting 1-related protein kinase (SnRK1) in the halophyte ice plant.A modulatory role for clathrin light chain phosphorylation in Golgi membrane protein localization during vegetative growth and during the mating response of Saccharomyces cerevisiae.KEX2 influences Candida albicans proteinase secretion and hyphal formation.Yeast Golgi-localized, gamma-Ear-containing, ADP-ribosylation factor-binding proteins are but adaptor protein-1 is not required for cell-free transport of membrane proteins from the trans-Golgi network to the prevacuolar compartment.The yeast GRD20 gene is required for protein sorting in the trans-Golgi network/endosomal system and for polarization of the actin cytoskeleton.Skp1p regulates Soi3p/Rav1p association with endosomal membranes but is not required for vacuolar ATPase assembly.Quantitative high-content imaging identifies novel regulators of Neo1 trafficking at endosomes.Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth.A novel syntaxin 6-interacting protein, SHIP164, regulates syntaxin 6-dependent sorting from early endosomes.Mutational spectrum of COH1 and clinical heterogeneity in Cohen syndrome.Cargo selectivity of yeast sorting nexins.Retrograde trafficking from the endosome to the trans-Golgi network mediated by the retromer is required for fungal development and pathogenicity in Fusarium graminearum.
P2860
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P2860
Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins.
description
1996 nî lūn-bûn
@nan
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Allele-specific suppression of ...... of TGN transmembrane proteins.
@ast
Allele-specific suppression of ...... of TGN transmembrane proteins.
@en
Allele-specific suppression of ...... of TGN transmembrane proteins.
@nl
type
label
Allele-specific suppression of ...... of TGN transmembrane proteins.
@ast
Allele-specific suppression of ...... of TGN transmembrane proteins.
@en
Allele-specific suppression of ...... of TGN transmembrane proteins.
@nl
prefLabel
Allele-specific suppression of ...... of TGN transmembrane proteins.
@ast
Allele-specific suppression of ...... of TGN transmembrane proteins.
@en
Allele-specific suppression of ...... of TGN transmembrane proteins.
@nl
P2093
P2860
P356
P1476
Allele-specific suppression of ...... of TGN transmembrane proteins.
@en
P2093
J H Brickner
J W Nichols
L G Marschall
R S Fuller
P2860
P304
P356
10.1128/MCB.16.11.6208
P407
P577
1996-11-01T00:00:00Z