SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals.
about
Cohen syndrome is caused by mutations in a novel gene, COH1, encoding a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transportThe yeast mutant vps5Delta affected in the recycling of Golgi membrane proteins displays an enhanced vacuolar Mg2+/H+ exchange activityDistinct domains within Vps35p mediate the retrieval of two different cargo proteins from the yeast prevacuolar/endosomal compartmentSfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplicationDisease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activationSla1p serves as the targeting signal recognition factor for NPFX(1,2)D-mediated endocytosis.Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomesRic1p and the Ypt6p GTPase function in a common pathway required for localization of trans-Golgi network membrane proteinsYeast Vps13 promotes mitochondrial function and is localized at membrane contact sites.VPS13 regulates membrane morphogenesis during sporulation in Saccharomyces cerevisiae.Ypt31/32 GTPases and their novel F-box effector protein Rcy1 regulate protein recyclingProtein kinases Fpk1p and Fpk2p are novel regulators of phospholipid asymmetry.SPO71 encodes a developmental stage-specific partner for Vps13 in Saccharomyces cerevisiae.Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1.A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal traffickingSpecific retrieval of the exocytic SNARE Snc1p from early yeast endosomes.ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13.The amino-terminal domain of the vacuolar proton-translocating ATPase a subunit controls targeting and in vivo dissociation, and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis.Purification and characterization of the yeast glycosylphosphatidylinositol-anchored, monobasic-specific aspartyl protease yapsin 2 (Mkc7p).Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteinsThe Dysferlin Domain-Only Protein, Spo73, Is Required for Prospore Membrane Extension in Saccharomyces cerevisiaeThe yeast GTPase Mtg2p is required for mitochondrial translation and partially suppresses an rRNA methyltransferase mutant, mrm2Cdk phosphorylation of a nucleoporin controls localization of active genes through the cell cycle.Endocytic recycling in yeast is regulated by putative phospholipid translocases and the Ypt31p/32p-Rcy1p pathway.TipC and the chorea-acanthocytosis protein VPS13A regulate autophagy in Dictyostelium and human HeLa cellsA gene-targeted mouse model for chorea-acanthocytosisLipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells.H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state.Amino acid substitution equivalent to human chorea-acanthocytosis I2771R in yeast Vps13 protein affects its binding to phosphatidylinositol 3-phosphate.Vps13F links bacterial recognition and intracellular killing in DictyosteliumA dileucine-like sorting signal directs transport into an AP-3-dependent, clathrin-independent pathway to the yeast vacuoleAllelic heterogeneity in the COH1 gene explains clinical variability in Cohen syndrome.Golgi-to-late endosome trafficking of the yeast pheromone processing enzyme Ste13p is regulated by a phosphorylation site in its cytosolic domainA novel mechanism for localizing membrane proteins to yeast trans-Golgi network requires function of synaptojanin-like protein.Brain, blood, and iron: perspectives on the roles of erythrocytes and iron in neurodegeneration.Cohen syndrome-associated protein, COH1, is a novel, giant Golgi matrix protein required for Golgi integrityExpression of insulin in yeast: the importance of molecular adaptation for secretion and conversion.pH-dependent cargo sorting from the Golgi.Vps10p transport from the trans-Golgi network to the endosome is mediated by clathrin-coated vesiclesDefective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.
P2860
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P2860
SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals.
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@ast
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@en
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@nl
type
label
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@ast
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@en
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@nl
prefLabel
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@ast
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@en
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@nl
P2860
P3181
P356
P1476
SOI1 encodes a novel, conserve ...... two TGN localization signals.
@en
P2093
J H Brickner
R S Fuller
P2860
P3181
P356
10.1083/JCB.139.1.23
P407
P577
1997-10-06T00:00:00Z