Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants
about
The proteins PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA exportATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complexEngineering a two-helix bundle protein for folding studiesAn hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.The role of TREX in gene expression and diseaseThe closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progressionDeterminants of protein abundance and translation efficiency in S. cerevisiaeNab2 functions in the metabolism of RNA driven by polymerases II and III.Following temperature stress, export of heat shock mRNA occurs efficiently in cells with mutations in genes normally important for mRNA export.High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1.Co-transcriptional mRNP formation is coordinated within a molecular mRNP packaging station in S. cerevisiaeCip29 is phosphorylated following activation of the DNA damage response in Xenopus egg extracts.Multifunctional factor ENY2 is associated with the THO complex and promotes its recruitment onto nascent mRNA.R-loops do not accumulate in transcription-defective hpr1-101 mutants: implications for the functional role of THO/TREX.mRNA export: threading the needle.Human THO-Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability.Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability.The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.A screening method tuned for mRNA processing factors in human cells by evaluation of the luciferase reporter activity and the subcellular distribution of bulk poly(A)+ RNA.
P2860
Q24297677-1ACB0D85-C29F-4EDD-9639-26930C2CA44DQ24299834-D777772E-26E2-4E64-8A8B-A0916EA09D42Q27659490-1273F030-7AE6-47A8-A7D5-2378A44F101EQ27931955-B90CA3CD-DB89-4E02-918F-FBE723065632Q28078160-5EF0396E-A994-4F22-8532-89FA831C9BDDQ30496034-295F6C7E-1A83-47B4-BAE4-9061CDF7D07DQ30839811-A13FFD2D-2519-4FE6-BF6D-3A04FF6F590AQ35133617-E4DF85AF-DF18-4388-B955-165DBD5F44E8Q35690220-236A7160-6302-4105-8A41-829E3AD40B17Q36052697-6AA23478-24C5-4A75-AFC7-78B0C8510322Q38388224-2C496449-6737-4A77-BFC3-32FBF71F1B95Q38675646-A03C4B59-D78C-479A-82A6-980C022119F5Q42114689-B018CDBB-12EE-4C19-8580-EDAA95D6B50EQ42574551-C431329C-75B0-4C8A-8A96-45F48B79D077Q43219557-2103D472-BEF5-4FCB-A57A-AE3C7F70743CQ47598135-0DECC889-C744-4DEF-919D-CB4415E7652AQ47705341-17541C6F-5329-413F-A1CF-1E0A5AA813ACQ51243304-1148A52B-FDCE-484D-A7A0-F3839CE32ACAQ53313232-A4FDEB37-41AA-4FEF-A3E5-40E54388EAB0
P2860
Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Tho1, a novel hnRNP, and Sub2 ...... iogenesis in yeast THO mutants
@ast
Tho1, a novel hnRNP, and Sub2 ...... iogenesis in yeast THO mutants
@en
Tho1, a novel hnRNP, and Sub2 ...... ogenesis in yeast THO mutants.
@nl
type
label
Tho1, a novel hnRNP, and Sub2 ...... iogenesis in yeast THO mutants
@ast
Tho1, a novel hnRNP, and Sub2 ...... iogenesis in yeast THO mutants
@en
Tho1, a novel hnRNP, and Sub2 ...... ogenesis in yeast THO mutants.
@nl
prefLabel
Tho1, a novel hnRNP, and Sub2 ...... iogenesis in yeast THO mutants
@ast
Tho1, a novel hnRNP, and Sub2 ...... iogenesis in yeast THO mutants
@en
Tho1, a novel hnRNP, and Sub2 ...... ogenesis in yeast THO mutants.
@nl
P2860
P50
P3181
P356
P1476
Tho1, a novel hnRNP, and Sub2 ...... iogenesis in yeast THO mutants
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.00234-06
P407
P577
2006-06-01T00:00:00Z