Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.
about
Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipidsThe eisosome core is composed of BAR domain proteins.The mTOR signalling pathway in human cancerTargeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapyPhosphoinositides: tiny lipids with giant impact on cell regulationInsights into eisosome assembly and organizationPhosphoinositide kinase signaling controls ER-PM cross-talk.Structural Analyses of the Slm1-PH Domain Demonstrate Ligand Binding in the Non-Canonical SiteA conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.Molecular organization of target of rapamycin complex 2.Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2.Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane.Requirements of Slm proteins for proper eisosome organization, endocytic trafficking and recycling in the yeast Saccharomyces cerevisiae.Calmodulin dissociation regulates Myo5 recruitment and function at endocytic sites.TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain.Yeast Arf3p modulates plasma membrane PtdIns(4,5)P2 levels to facilitate endocytosis.The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress.The phosphoinositide phosphatase Sjl2 is recruited to cortical actin patches in the control of vesicle formation and fission during endocytosis.The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2.Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiaeProtor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidneyA neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeastCell growth control: little eukaryotes make big contributions.The application of RAGE and GECKO in cell-based target discovery screens.Global screening of genes essential for growth in high-pressure and cold environments: searching for basic adaptive strategies using a yeast deletion libraryCell wall integrity signaling in Saccharomyces cerevisiaeInterruption of inositol sphingolipid synthesis triggers Stt4p-dependent protein kinase C signaling.Screening the budding yeast genome reveals unique factors affecting K2 toxin susceptibility.Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease.Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast.Target of rapamycin (TOR) in nutrient signaling and growth controlCentral roles of small GTPases in the development of cell polarity in yeast and beyond.Cell-free reconstitution of vacuole membrane fragmentation reveals regulation of vacuole size and number by TORC1.Target of rapamycin complex 2 signals to downstream effector yeast protein kinase 2 (Ypk2) through adheres-voraciously-to-target-of-rapamycin-2 protein 1 (Avo1) in Saccharomyces cerevisiae.TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiaeDetermining selectivity of phosphoinositide-binding domains
P2860
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P2860
Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@ast
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@en
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@nl
type
label
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@ast
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@en
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@nl
prefLabel
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@ast
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@en
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@nl
P2093
P2860
P356
P1433
P1476
Genome-wide lethality screen i ...... gulate the actin cytoskeleton.
@en
P2093
Ainslie B Parsons
Anjon Audhya
Charles Boone
Michael N Hall
Mitsuaki Tabuchi
Scott D Emr
P2860
P304
P356
10.1038/SJ.EMBOJ.7600384
P407
P577
2004-09-16T00:00:00Z