Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
about
The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex componentsActive-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9Structural analysis and functional implications of the negative mTORC1 regulator REDD1Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycinmTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4EIdentification of Protor as a novel Rictor-binding component of mTOR complex-2Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitiveRab1A is an mTORC1 activator and a colorectal oncogeneCCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signalingEssential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signallingPRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.Signaling by target of rapamycin proteins in cell growth controlNutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylationDisruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell developmentmTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cellsThe TOR pathway comes of ageNaturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanismUpdates of mTOR inhibitorsResveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTORSpatial regulation of the mTORC1 system in amino acids sensing pathwayThe mTOR signalling pathway in human cancerAn emerging role for TOR signaling in mammalian tissue and stem cell physiologyTargeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapyReduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expressionmTOR: from growth signal integration to cancer, diabetes and ageingMolecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1The TSC1-TSC2 complex: a molecular switchboard controlling cell growthRegulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylationIdentification of Sin1 as an essential TORC2 component required for complex formation and kinase activityRank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling dataThe evolution of the Sin1 gene product, a little known protein implicated in stress responses and type I interferon signaling in vertebratesThe Arabidopsis Mei2 homologue AML1 binds AtRaptor1B, the plant homologue of a major regulator of eukaryotic cell growthThe Arabidopsis AtRaptor genes are essential for post-embryonic plant growthHuman Cytomegalovirus Strategies to Maintain and Promote mRNA TranslationBiochemical Genetic Pathways that Modulate Aging in Multiple Species
P2860
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
P248
Q21144957-C7B8DC20-87DF-4F6E-A923-D6C5E507CA95Q21145847-C9B2CFD5-3814-40FD-8913-678AD1F638FFQ21563331-39F2A96E-07F6-4366-ACB6-215A15948E4BQ24300025-09B181BC-16B9-47A2-A6BF-6DB1429E6940Q24301667-6EF90EC0-D139-4BD6-BAD4-D67C0D728910Q24301780-DB8BBE5D-5EB8-4AD8-87BF-000F19A90DBDQ24303936-228ACE53-119A-41CC-8925-1E4A9BD14073Q24306328-144EA799-E8CE-4032-925B-F5CBDA2A5902Q24307749-7CB255F4-C18A-485B-89E9-3A18C97F0970Q24310613-901A3839-7276-47A4-B731-834F95B67BACQ24315566-A7E3E46D-702C-4025-B4EE-71833A28980DQ24320106-62C50ACF-C768-469D-B59D-5943513EC9AFQ24323370-DD8F537E-1CA5-4A0D-A786-E10438E64609Q24323912-A64D5734-1F03-499D-8627-4581BC169AE8Q24519078-8EF08724-021E-476C-8320-F6C61EDAA5ACQ24522447-39F8253B-6799-468A-888D-93B93252B175Q24535576-B9F13C18-5A41-4DA9-803A-1594EEC56000Q24563399-C56FA1C3-1739-475B-B076-6B49CBDD1EB5Q24564276-E9542617-5B94-4680-AEE8-FDAFAE028ADBQ24568353-369AD233-135C-4D90-97B7-9D18B8ADB25EQ24595310-3ED40847-B7CD-4178-A90B-C72C505D9980Q24607170-52071CB1-70B0-4AC5-AC6A-10A9775DD4E9Q24608321-5C640035-D52C-43EF-8385-940C8DE20F41Q24612853-D1C7D964-6C50-41D5-8DBD-9C1A1E5CBE07Q24627306-F4009FEF-2825-4D50-A8D5-01A4E2756DEAQ24629305-D5E22790-A147-4465-B211-F67F111BE29FQ24632296-445F3823-DB4C-436B-8087-C5AB987B422CQ24633031-BE3F084C-C27C-4539-90CD-6C581941E6B9Q24633662-B7071BF9-0588-4399-BE06-A216294BDCA3Q24633947-A11F3AA9-68BA-49F6-B8F9-87E2D76FF4D7Q24645183-F09B64E9-C1BC-4D3D-B3CF-130310091534Q24645204-9B493430-5E15-4DFA-ACDC-F12198E12BF4Q24648213-94CF6815-5775-40E0-9FD0-1FBBEA1BC99AQ24680264-FDBB1C91-A8EA-44C8-B898-1DE8B4FF7AD1Q24791590-5D6A1E2D-7BA9-4A33-A9DF-FE2E56E854CAQ24793262-8BE86510-ECC8-45A2-9479-00C410A1257DQ24799601-E9C87E9E-4974-4C2A-8ED4-261E71B16D59Q24804818-903919D8-870A-4948-9F9E-FC908C359F66Q26752742-9D744853-E245-4D61-9574-954F6EB723E6Q26777407-F02DCDBF-8B7C-4B37-A639-F449A2E69DC1
P2860
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Two TOR complexes, only one of ...... t roles in cell growth control
@ast
Two TOR complexes, only one of ...... t roles in cell growth control
@en
Two TOR complexes, only one of ...... t roles in cell growth control
@en-gb
Two TOR complexes, only one of ...... t roles in cell growth control
@nl
type
label
Two TOR complexes, only one of ...... t roles in cell growth control
@ast
Two TOR complexes, only one of ...... t roles in cell growth control
@en
Two TOR complexes, only one of ...... t roles in cell growth control
@en-gb
Two TOR complexes, only one of ...... t roles in cell growth control
@nl
prefLabel
Two TOR complexes, only one of ...... t roles in cell growth control
@ast
Two TOR complexes, only one of ...... t roles in cell growth control
@en
Two TOR complexes, only one of ...... t roles in cell growth control
@en-gb
Two TOR complexes, only one of ...... t roles in cell growth control
@nl
P2093
P50
P3181
P1433
P1476
Two TOR complexes, only one of ...... t roles in cell growth control
@en
P2093
Anja Lorberg
Débora Bonenfant
Michael N Hall
Paul Jenoe
Wolfgang Oppliger
P304
P3181
P356
10.1016/S1097-2765(02)00636-6
P407
P577
2002-09-01T00:00:00Z