Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3.
about
Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombinationMammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repairHuman SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleasesA tale of tails: insights into the coordination of 3' end processing during homologous recombinationDisruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemiaEvidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.Hold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1Nucleases in homologous recombination as targets for cancer therapyMechanisms and regulation of mitotic recombination in Saccharomyces cerevisiaeMechanism and regulation of incisions during DNA interstrand cross-link repairSmc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisionsMammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesisCaenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediatesHpy188I-DNA pre- and post-cleavage complexes--snapshots of the GIY-YIG nuclease mediated catalysisEsc4/Rtt107 and the control of recombination during replication.Genetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast.Budding Yeast SLX4 Contributes to the Appropriate Distribution of Crossovers and Meiotic Double-Strand Break Formation on Bivalents During Meiosis.Rmi1, a member of the Sgs1-Top3 complex in budding yeast, contributes to sister chromatid cohesionMicroarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediatesRole of Saw1 in Rad1/Rad10 complex assembly at recombination intermediates in budding yeastA genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair.Genetic instability in budding and fission yeast-sources and mechanismsDelineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvaseTemporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctionsAssembly of Slx4 signaling complexes behind DNA replication forksSaccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activitiesPhylogenomic analysis of the GIY-YIG nuclease superfamily.Rtt107/Esc4 binds silent chromatin and DNA repair proteins using different BRCT motifs.Inferring transcriptional compensation interactions in yeast via stepwise structure equation modelingSmc5/6 maintains stalled replication forks in a recombination-competent conformation.Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis.Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates.GEN1/Yen1 and the SLX4 complex: Solutions to the problem of Holliday junction resolution.Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes.Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila.Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathwaySlx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4SLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germline.Recombination and replication.
P2860
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P248
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P2860
Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@ast
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@en
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@nl
type
label
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@ast
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@en
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@nl
prefLabel
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@ast
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@en
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@nl
P2860
P3181
P356
P1433
P1476
Slx1-Slx4 is a second structur ...... ally redundant with Sgs1-Top3.
@en
P2093
Steven J Brill
William M Fricke
P2860
P304
P3181
P356
10.1101/GAD.1105203
P407
P577
2003-07-15T00:00:00Z