Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.
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The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phaseHexameric ring structure of human MCM10 DNA replication factorInvolvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatinMinichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinasesDrosophila double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcriptsGenome-wide comprehensive analysis of human helicasesATP bound to the origin recognition complex is important for preRC formationDomain architecture and biochemical characterization of vertebrate Mcm10Structural basis for DNA binding by replication initiator Mcm10An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexesDrosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensationReconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteinsNuclear distribution and chromatin association of DNA polymerase alpha-primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast.Physical Interactions between Mcm10, DNA, and DNA PolymeraseSolution NMR Structure of the C-terminal DNA Binding Domain of Mcm10 Reveals a Conserved MCM MotifMcm10 Self-Association Is Mediated by an N-Terminal Coiled-Coil DomainMcm10 is required for the maintenance of transcriptional silencing in Saccharomyces cerevisiae.Mcm10 mediates the interaction between DNA replication and silencing machineriesMcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation.A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome.Novel DNA binding properties of the Mcm10 protein from Saccharomyces cerevisiae.Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeastMechanisms Governing DDK Regulation of the Initiation of DNA ReplicationEukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases.Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae.Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the central zinc-binding domain of the human Mcm10 DNA-replication factorUltraviolet radiation stress triggers the down-regulation of essential replication factor Mcm10.Mcm10 proteolysis initiates before the onset of M-phase.DNA replication forks pause at silent origins near the HML locus in budding yeastCharacterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA.Multiple functions for Drosophila Mcm10 suggested through analysis of two Mcm10 mutant allelesUbc4 and Not4 regulate steady-state levels of DNA polymerase-α to promote efficient and accurate DNA replication.Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG componentsCharacterization of Schizosaccharomyces pombe mcm7(+) and cdc23(+) (MCM10) and interactions with replication checkpoints.MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replicationEukaryotic MCM proteins: beyond replication initiation.Stepwise assembly of initiation proteins at budding yeast replication origins in vitro.HIV-1 Vpr Protein Enhances Proteasomal Degradation of MCM10 DNA Replication Factor through the Cul4-DDB1[VprBP] E3 Ubiquitin Ligase to Induce G2/M Cell Cycle Arrest.Mcm10 coordinates the timely assembly and activation of the replication fork helicase.A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication
P2860
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P2860
Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.
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2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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Mcm10 and the MCM2-7 complex i ...... lication factors from origins.
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Mcm10 and the MCM2-7 complex i ...... lication factors from origins.
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Mcm10 and the MCM2-7 complex i ...... lication factors from origins.
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Mcm10 and the MCM2-7 complex i ...... lication factors from origins.
@ast
Mcm10 and the MCM2-7 complex i ...... lication factors from origins.
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Mcm10 and the MCM2-7 complex i ...... lication factors from origins.
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Mcm10 and the MCM2-7 complex i ...... lication factors from origins.
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Mcm10 and the MCM2-7 complex i ...... lication factors from origins.
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Mcm10 and the MCM2-7 complex i ...... lication factors from origins.
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Mcm10 and the MCM2-7 complex i ...... plication factors from origins
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2000-04-01T00:00:00Z