Identification of a UPC2 homolog in Saccharomyces cerevisiae and its involvement in aerobic sterol uptake
about
Dual activators of the sterol biosynthetic pathway of Saccharomyces cerevisiae: similar activation/regulatory domains but different response mechanisms.The zinc cluster proteins Upc2 and Ecm22 promote filamentation in Saccharomyces cerevisiae by sterol biosynthesis-dependent and -independent pathways.A role for sterol levels in oxygen sensing in Saccharomyces cerevisiae.Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae.Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae.The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway.A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatusA predictive model of the oxygen and heme regulatory network in yeastTranscriptional responses of Saccharomyces cerevisiae to shift from respiratory and respirofermentative to fully fermentative metabolism.Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae.UPC2A is required for high-level azole antifungal resistance in Candida glabrata.Cumulative mutations affecting sterol biosynthesis in the yeast Saccharomyces cerevisiae result in synthetic lethality that is suppressed by alterations in sphingolipid profiles.Crystallization and preliminary X-ray crystallographic analysis of sterol transcription factor Upc2 from Saccharomyces cerevisiae.A fungal family of transcriptional regulators: the zinc cluster proteinsH3K4 methyltransferase Set1 is involved in maintenance of ergosterol homeostasis and resistance to Brefeldin A.A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.Comparison of sterol import under aerobic and anaerobic conditions in three fungal species, Candida albicans, Candida glabrata, and Saccharomyces cerevisiae.Novel antifungal drug discovery based on targeting pathways regulating the fungus-conserved Upc2 transcription factorTime-Course Analysis of Gene Expression During the Saccharomyces cerevisiae Hypoxic Response.SUT1-promoted sterol uptake involves the ABC transporter Aus1 and the mannoprotein Dan1 whose synergistic action is sufficient for this processFrom Lipid Homeostasis to Differentiation: Old and New Functions of the Zinc Cluster Proteins Ecm22, Upc2, Sut1 and Sut2.The Candida albicans lanosterol 14-alpha-demethylase (ERG11) gene promoter is maximally induced after prolonged growth with antifungal drugsRole of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolismCandida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes.Learning regulatory programs that accurately predict differential expression with MEDUSA.Structural mechanism of ergosterol regulation by fungal sterol transcription factor Upc2.Building terpene production platforms in yeast.
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P2860
Identification of a UPC2 homolog in Saccharomyces cerevisiae and its involvement in aerobic sterol uptake
description
2001 nî lūn-bûn
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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
@zh-hk
2001年論文
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2001年論文
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2001年论文
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name
Identification of a UPC2 homol ...... ement in aerobic sterol uptake
@ast
Identification of a UPC2 homol ...... ement in aerobic sterol uptake
@en
Identification of a UPC2 homol ...... ment in aerobic sterol uptake.
@nl
type
label
Identification of a UPC2 homol ...... ement in aerobic sterol uptake
@ast
Identification of a UPC2 homol ...... ement in aerobic sterol uptake
@en
Identification of a UPC2 homol ...... ment in aerobic sterol uptake.
@nl
prefLabel
Identification of a UPC2 homol ...... ement in aerobic sterol uptake
@ast
Identification of a UPC2 homol ...... ement in aerobic sterol uptake
@en
Identification of a UPC2 homol ...... ment in aerobic sterol uptake.
@nl
P2093
P2860
P1476
Identification of a UPC2 homol ...... ement in aerobic sterol uptake
@en
P2093
P2860
P304
P356
10.1128/JB.183.3.830-834.2001
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P50
P577
2001-02-01T00:00:00Z