Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity
about
The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis.Iron, glucose and intrinsic factors alter sphingolipid composition as yeast cells enter stationary phase.Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene.Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast.Syringomycin action gene SYR2 is essential for sphingolipid 4-hydroxylation in Saccharomyces cerevisiae.The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3-ketosphinganine reductase is identified in a screen for temperature-sensitive suppressors of the Ca2+-sensitive csg2Delta mutant.Plasmodium falciparum phospholipase C hydrolyzing sphingomyelin and lysocholinephospholipids is a possible target for malaria chemotherapyPhospholipid and sphingolipid metabolism in Leishmania.Lipid remodeling leads to the introduction and exchange of defined ceramides on GPI proteins in the ER and Golgi of Saccharomyces cerevisiae.Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazoleDe novo synthesis of sphingolipids is required for cell survival by down-regulating c-Jun N-terminal kinase in Drosophila imaginal discs.The yeast sphingolipid signaling landscape.Yeast sphingolipids: recent developments in understanding biosynthesis, regulation, and function.Modulation of sphingolipid metabolism by the phosphatidylinositol-4-phosphate phosphatase Sac1p through regulation of phosphatidylinositol in Saccharomyces cerevisiae.Yeast sphingolipid metabolism: clues and connections.Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift.Identification of a Saccharomyces gene, LCB3, necessary for incorporation of exogenous long chain bases into sphingolipids.Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexansSphingolipids are essential for differentiation but not growth in LeishmaniaRole of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in GlucosylceramideEstablishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs.Membrane engineering of S. cerevisiae targeting sphingolipid metabolism.Sphingolipid metabolism and interorganellar transport: localization of sphingolipid enzymes and lipid transfer proteins.Sphingolipid long-chain-base auxotrophs of Saccharomyces cerevisiae: genetics, physiology, and a method for their selection.Phenotypes of sphingolipid-dependent strains of Saccharomyces cerevisiaeThe plasma membrane of Saccharomyces cerevisiae: structure, function, and biogenesis.Ceramide synthesis enhances transport of GPI-anchored proteins to the Golgi apparatus in yeast.Ceramide signals for initiation of yeast mating-specific cell cycle arrest.Neutral sphingomyelinase activity dependent on Mg2+ and anionic phospholipids in the intraerythrocytic malaria parasite Plasmodium falciparum.The Sphingolipid Biosynthetic Pathway Is a Potential Target for Chemotherapy against Chagas Disease.Quantification of 3-ketodihydrosphingosine using HPLC-ESI-MS/MS to study SPT activity in yeast Saccharomyces cerevisiae.Selective substrate supply in the regulation of yeast de novo sphingolipid synthesis.Biological Roles Played by Sphingolipids in Dimorphic and Filamentous Fungi.
P2860
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P2860
Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity
description
1992 nî lūn-bûn
@nan
1992 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Characterization of enzymatic ...... palmitoyltransferase activity
@ast
Characterization of enzymatic ...... palmitoyltransferase activity
@en
Characterization of enzymatic ...... palmitoyltransferase activity.
@nl
type
label
Characterization of enzymatic ...... palmitoyltransferase activity
@ast
Characterization of enzymatic ...... palmitoyltransferase activity
@en
Characterization of enzymatic ...... palmitoyltransferase activity.
@nl
altLabel
Characterization of enzymatic ...... palmitoyltransferase activity
@en
prefLabel
Characterization of enzymatic ...... palmitoyltransferase activity
@ast
Characterization of enzymatic ...... palmitoyltransferase activity
@en
Characterization of enzymatic ...... palmitoyltransferase activity.
@nl
P2093
P2860
P3181
P1476
Characterization of enzymatic ...... palmitoyltransferase activity
@en
P2093
P2860
P304
P3181
P356
10.1128/JB.174.8.2575-2581.1992
P407
P577
1992-04-01T00:00:00Z