Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids.
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Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificitiesThe essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferaseSphingolipidomics: An Important Mechanistic Tool for Studying Fungal PathogensThe External Aldimine Form of Serine Palmitoyltransferase: STRUCTURAL, KINETIC, AND SPECTROSCOPIC ANALYSIS OF THE WILD-TYPE ENZYME AND HSAN1 MUTANT MIMICSStructural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorumThe LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis.Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activitySLI1 (YGR212W) is a major gene conferring resistance to the sphingolipid biosynthesis inhibitor ISP-1, and encodes an ISP-1 N-acetyltransferase in yeastPil1p and Lsp1p negatively regulate the 3-phosphoinositide-dependent protein kinase-like kinase Pkh1p and downstream signaling pathways Pkc1p and Ypk1p.Regulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene.The effect of the erg26-1 mutation on the regulation of lipid metabolism in Saccharomyces cerevisiae.Differential regulation of ceramide synthase components LAC1 and LAG1 in Saccharomyces cerevisiae.Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast.The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases.ATP uptake in the Golgi and extracellular release require Mcd4 protein and the vacuolar H+-ATPase.Syringomycin action gene SYR2 is essential for sphingolipid 4-hydroxylation in Saccharomyces cerevisiae.Identification and characterization of a Saccharomyces cerevisiae gene, RSB1, involved in sphingoid long-chain base release.Synthesis of mannose-(inositol-P)2-ceramide, the major sphingolipid in Saccharomyces cerevisiae, requires the IPT1 (YDR072c) gene.Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1.The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3-ketosphinganine reductase is identified in a screen for temperature-sensitive suppressors of the Ca2+-sensitive csg2Delta mutant.Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae.Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug actionDown-regulating sphingolipid synthesis increases yeast lifespanGenetic and genomic architecture of the evolution of resistance to antifungal drug combinationsMathematical modeling of pathogenicity of Cryptococcus neoformansThe plant decapeptide OSIP108 prevents copper-induced apoptosis in yeast and human cellsLipid remodeling leads to the introduction and exchange of defined ceramides on GPI proteins in the ER and Golgi of Saccharomyces cerevisiae.De novo synthesis of sphingolipids is required for cell survival by down-regulating c-Jun N-terminal kinase in Drosophila imaginal discs.The organizing potential of sphingolipids in intracellular membrane transport.Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae.Integrative transformation system for the metabolic engineering of the sphingoid base-producing yeast Pichia ciferrii.Molecular characterization of membrane-associated soluble serine palmitoyltransferases from Sphingobacterium multivorum and Bdellovibrio stolpiiL-serine in disease and developmentIncreased ubiquitin-dependent degradation can replace the essential requirement for heat shock protein induction.Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells.Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathwaysSphingolipids regulate the yeast high-osmolarity glycerol response pathway.Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated.
P2860
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P2860
Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Cloning and characterization o ...... se component of sphingolipids.
@en
Cloning and characterization o ...... se component of sphingolipids.
@nl
type
label
Cloning and characterization o ...... se component of sphingolipids.
@en
Cloning and characterization o ...... se component of sphingolipids.
@nl
prefLabel
Cloning and characterization o ...... se component of sphingolipids.
@en
Cloning and characterization o ...... se component of sphingolipids.
@nl
P2093
P2860
P1476
Cloning and characterization o ...... se component of sphingolipids.
@en
P2093
C Rinker-Schaffer
R C Dickson
R L Lester
P2860
P304
P356
10.1128/JB.173.14.4325-4332.1991
P577
1991-07-01T00:00:00Z