The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor
about
Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathwayA family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cellsThe N-end rule pathwayDiscovery of cellular regulation by protein degradationThe mouse and human genes encoding the recognition component of the N-end rule pathwayHarnessing natural diversity to probe metabolic pathwaysUbr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins.Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p.Physical association of ubiquitin ligases and the 26S proteasome.Differential regulation and substrate preferences in two peptide transporters of Saccharomyces cerevisiae.Suppressors of ssy1 and ptr3 null mutations define novel amino acid sensor-independent genes in Saccharomyces cerevisiae.Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter.Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.Identification of determinants in E2 ubiquitin-conjugating enzymes required for hect E3 ubiquitin-protein ligase interactionThe ubiquitin-proteasome pathway and proteasome inhibitorsThe ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule pathway, stabilizes Tex19.1 during spermatogenesisConstruction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathwayAltered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathwayGenomewide screen reveals a wide regulatory network for di/tripeptide utilization in Saccharomyces cerevisiae.From bacteria to man: archaic proton-dependent peptide transporters at work.Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic ratsDegradation or maintenance: actions of the ubiquitin system on eukaryotic chromatinFelix Hoppe-Seyler Lecture 2000. The ubiquitin system and the N-end rule pathway.The N-end rule pathway and regulation by proteolysisUBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells.Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain.Saccharomyces cerevisiae Ub-conjugating enzyme Ubc4 binds the proteasome in the presence of translationally damaged proteinsAnalysing the substrate multispecificity of a proton-coupled oligopeptide transporter using a dipeptide library.Differential adaptation to multi-stressed conditions of wine fermentation revealed by variations in yeast regulatory networks.Regulation of the Sre1 hypoxic transcription factor by oxygen-dependent control of DNA binding.Regulation of amino acid, nucleotide, and phosphate metabolism in Saccharomyces cerevisiae.Ubiquitin ligases in malignant lymphoma.Pharmacological Modulation of the N-End Rule Pathway and Its Therapeutic Implications.Rates of ubiquitin conjugation increase when muscles atrophy, largely through activation of the N-end rule pathwayKilling of macrophages by anthrax lethal toxin: involvement of the N-end rule pathway.Degradation elements coincide with cofactor binding sites in a short-lived transcription factor.Quorum sensing controls hyphal initiation in Candida albicans through Ubr1-mediated protein degradation.A new method for the selection of protein interactions in mammalian cells.
P2860
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P2860
The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The N-end rule pathway control ...... of a transcriptional repressor
@ast
The N-end rule pathway control ...... of a transcriptional repressor
@en
The N-end rule pathway control ...... f a transcriptional repressor.
@nl
type
label
The N-end rule pathway control ...... of a transcriptional repressor
@ast
The N-end rule pathway control ...... of a transcriptional repressor
@en
The N-end rule pathway control ...... f a transcriptional repressor.
@nl
prefLabel
The N-end rule pathway control ...... of a transcriptional repressor
@ast
The N-end rule pathway control ...... of a transcriptional repressor
@en
The N-end rule pathway control ...... f a transcriptional repressor.
@nl
P2860
P356
P1433
P1476
The N-end rule pathway control ...... of a transcriptional repressor
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/17.1.269
P407
P577
1998-01-01T00:00:00Z