GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae
about
Unanticipated antigens: translation initiation at CUG with leucineMutational analysis of mammalian translation initiation factor 5 (eIF5): role of interaction between the beta subunit of eIF2 and eIF5 in eIF5 function in vitro and in vivoCharacterization of mammalian eIF2A and identification of the yeast homologPhosphorylation of mammalian translation initiation factor 5 (eIF5) in vitro and in vivoMultiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation.Identification of a cis-acting element required for shunt-mediated translational initiation of the Sendai virus Y proteins.Functional elements in initiation factors 1, 1A, and 2β discriminate against poor AUG context and non-AUG start codonsThe archaeal eIF2 homologue: functional properties of an ancient translation initiation factor.Why is start codon selection so precise in eukaryotes?Initiation factor-independent translation mediated by the hepatitis C virus internal ribosome entry siteThe large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.Structure of the archaeal translation initiation factor aIF2 from Methanobacterium thermoautotrophicum: Implications for translation initiationEukaryotic initiation factor (eIF) 1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selectionStructure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP statesStructure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNAThe joining of ribosomal subunits in eukaryotes requires eIF5B.A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivoMammalian translation initiation factor eIF1 functions with eIF1A and eIF3 in the formation of a stable 40 S preinitiation complex.Sequential eukaryotic translation initiation factor 5 (eIF5) binding to the charged disordered segments of eIF4G and eIF2β stabilizes the 48S preinitiation complex and promotes its shift to the initiation mode.The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selectionRelated eIF3 subunits TIF32 and HCR1 interact with an RNA recognition motif in PRT1 required for eIF3 integrity and ribosome binding.Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAsEukaryotic translation initiation factor 5 functions as a GTPase-activating protein.Development and characterization of a reconstituted yeast translation initiation system.The beta subunit of eukaryotic translation initiation factor 2 binds mRNA through the lysine repeats and a region comprising the C2-C2 motif.Posttranscriptional control of gene expression in yeast.Nip1p associates with 40 S ribosomes and the Prt1p subunit of eukaryotic initiation factor 3 and is required for efficient translation initiation.Translation initiation at non-AUG codons mediated by weakened association of eukaryotic initiation factor (eIF) 2 subunits.Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation.Role of a short open reading frame in ribosome shunt on the cauliflower mosaic virus RNA leaderCwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission YeastMolecular mechanisms of translation initiation in eukaryotesCryo-EM study of start codon selection during archaeal translation initiationA subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met.RNA polymerase I-promoted HIS4 expression yields uncapped, polyadenylated mRNA that is unstable and inefficiently translated in Saccharomyces cerevisiae.Initiation of protein synthesis in mammalian cells with codons other than AUG and amino acids other than methionine.Identification of compounds that decrease the fidelity of start codon recognition by the eukaryotic translational machinery.Mutations in Caenorhabditis elegans eIF2beta permit translation initiation from non-AUG start codons.Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2.
P2860
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P2860
GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
GTP hydrolysis controls string ...... on in Saccharomyces cerevisiae
@ast
GTP hydrolysis controls string ...... on in Saccharomyces cerevisiae
@en
GTP hydrolysis controls string ...... n in Saccharomyces cerevisiae.
@nl
type
label
GTP hydrolysis controls string ...... on in Saccharomyces cerevisiae
@ast
GTP hydrolysis controls string ...... on in Saccharomyces cerevisiae
@en
GTP hydrolysis controls string ...... n in Saccharomyces cerevisiae.
@nl
prefLabel
GTP hydrolysis controls string ...... on in Saccharomyces cerevisiae
@ast
GTP hydrolysis controls string ...... on in Saccharomyces cerevisiae
@en
GTP hydrolysis controls string ...... n in Saccharomyces cerevisiae.
@nl
P2093
P2860
P3181
P356
P1433
P1476
GTP hydrolysis controls string ...... on in Saccharomyces cerevisiae
@en
P2093
P2860
P304
P3181
P356
10.1101/GAD.11.18.2396
P407
P577
1997-09-01T00:00:00Z