Functional elements in initiation factors 1, 1A, and 2β discriminate against poor AUG context and non-AUG start codons
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Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5Why is start codon selection so precise in eukaryotes?'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)A mechanistic overview of translation initiation in eukaryotesTranslation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity.Eukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating Pi release and conformational transitions of the preinitiation complexThe mechanism of eukaryotic translation initiation: new insights and challengesGlobal mapping of translation initiation sites in mammalian cells at single-nucleotide resolution.The stringency of start codon selection in the filamentous fungus Neurospora crassa.Regulation of translation by upstream translation initiation codons of surfactant protein A1 splice variants.The β-hairpin of 40S exit channel protein Rps5/uS7 promotes efficient and accurate translation initiation in vivo.Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2βCoordinated movements of eukaryotic translation initiation factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in response to start codon recognition by the ribosomal preinitiation complexRoles of helicases in translation initiation: a mechanistic view.Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae.Systematic analysis of the PTEN 5' leader identifies a major AUU initiated proteoform.Architecture of human translation initiation factor 3.Interaction between 25S rRNA A loop and eukaryotic translation initiation factor 5B promotes subunit joining and ensures stringent AUG selection.β-Hairpin loop of eukaryotic initiation factor 1 (eIF1) mediates 40 S ribosome binding to regulate initiator tRNA(Met) recruitment and accuracy of AUG selection in vivo.eIF1A/eIF5B interaction network and its functions in translation initiation complex assembly and remodeling.Enhanced eIF1 binding to the 40S ribosome impedes conformational rearrangements of the preinitiation complex and elevates initiation accuracy.The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes.Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling.Interface between 40S exit channel protein uS7/Rps5 and eIF2α modulates start codon recognition in vivoNew insights into translational regulation in the endoplasmic reticulum unfolded protein response.Selective mRNA translation in erythropoiesis.Influence of translation factor activities on start site selection in six different mRNAs.Autoantibody response to Sui1 and its tissue-specific expression in hepatocellular carcinoma.Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons.Competition between translation initiation factor eIF5 and its mimic protein 5MP determines non-AUG initiation rate genome-wide.eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast.Non-AUG translation: a new start for protein synthesis in eukaryotes.eIF1 Loop 2 interactions with Met-tRNAi control the accuracy of start codon selection by the scanning preinitiation complex.Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection.Human eIF5 and eIF1A Compete for Binding to eIF5B
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P2860
Functional elements in initiation factors 1, 1A, and 2β discriminate against poor AUG context and non-AUG start codons
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Functional elements in initiat ...... ntext and non-AUG start codons
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Functional elements in initiat ...... ntext and non-AUG start codons
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Functional elements in initiat ...... ntext and non-AUG start codons
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Functional elements in initiat ...... ntext and non-AUG start codons
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Functional elements in initiat ...... ntext and non-AUG start codons
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Functional elements in initiat ...... ntext and non-AUG start codons
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prefLabel
Functional elements in initiat ...... ntext and non-AUG start codons
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Functional elements in initiat ...... ntext and non-AUG start codons
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Functional elements in initiat ...... ntext and non-AUG start codons
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P2093
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Functional elements in initiat ...... ntext and non-AUG start codons
@en
P2093
Alan G Hinnebusch
Pilar Martin-Marcos
Yuen-Nei Cheung
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P304
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P356
10.1128/MCB.05819-11
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P577
2011-12-01T00:00:00Z