Interaction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection.
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The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5' splice sites.U2 small nuclear ribonucleoprotein particle (snRNP) auxiliary factor of 65 kDa, U2AF65, can promote U1 snRNP recruitment to 5' splice sitesNext-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequenceThe U1 snRNP-associated factor Luc7p affects 5' splice site selection in yeast and humanExtended base pair complementarity between U1 snRNA and the 5' splice site does not inhibit splicing in higher eukaryotes, but rather increases 5' splice site recognitionPrp40 and early events in splice site definitionStructure of the yeast Pml1 splicing factor and its integration into the RES complexPub1p C-Terminal RRM Domain Interacts with Tif4631p through a Conserved Region Neighbouring the Pab1p Binding SiteEvidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4.Integration of a splicing regulatory network within the meiotic gene expression program of Saccharomyces cerevisiaeYeast ntr1/spp382 mediates prp43 function in postspliceosomes.Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complexThe U1 snRNP protein U1C recognizes the 5' splice site in the absence of base pairing.A targeted bypass screen identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for stable U1 snRNP/Pre-mRNA interaction.SRC1: an intron-containing yeast gene involved in sister chromatid segregation.prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeastA BBP-Mud2p heterodimer mediates branchpoint recognition and influences splicing substrate abundance in budding yeast.Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition.An essential role for trimethylguanosine RNA caps in Saccharomyces cerevisiae meiosis and their requirement for splicing of SAE3 and PCH2 meiotic pre-mRNAsRapid screening of yeast mutants with reporters identifies new splicing phenotypes.TIA-1 and TIAR activate splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on their own pre-mRNAsIdentification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in DrosophilaATP-dependent interaction of yeast U5 snRNA loop 1 with the 5' splice site.Yeast U1 snRNP-pre-mRNA complex formation without U1snRNA-pre-mRNA base pairing.The RNA-binding protein TIA-1 is a novel mammalian splicing regulator acting through intron sequences adjacent to a 5' splice siteThe pivotal roles of TIA proteins in 5' splice-site selection of alu exons and across evolutionPre-messenger RNA processing factors in the Drosophila genome.Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana.Selection of alternative 5' splice sites: role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1.iCLIP predicts the dual splicing effects of TIA-RNA interactions.Splicing of the meiosis-specific HOP2 transcript utilizes a unique 5' splice site.Aberrant splicing of tau pre-mRNA caused by intronic mutations associated with the inherited dementia frontotemporal dementia with parkinsonism linked to chromosome 17.Splicing enhancement in the yeast rp51b intron.The sequence complementarity between HIV-1 5' splice site SD4 and U1 snRNA determines the steady-state level of an unstable env pre-mRNA.Modulation of msl-2 5' splice site recognition by Sex-lethalAn in vitro-selected RNA-binding site for the KH domain protein PSI acts as a splicing inhibitor element.The Drosophila fl(2)d gene, required for female-specific splicing of Sxl and tra pre-mRNAs, encodes a novel nuclear protein with a HQ-rich domain.Determinants of Nam8-dependent splicing of meiotic pre-mRNAs.Multiple roles for the yeast SUB2/yUAP56 gene in splicingWidespread use of non-productive alternative splice sites in Saccharomyces cerevisiae
P2860
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P2860
Interaction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Interaction of the U1 snRNP wi ...... ects 5' splice site selection.
@ast
Interaction of the U1 snRNP wi ...... ects 5' splice site selection.
@en
Interaction of the U1 snRNP wi ...... ects 5' splice site selection.
@nl
type
label
Interaction of the U1 snRNP wi ...... ects 5' splice site selection.
@ast
Interaction of the U1 snRNP wi ...... ects 5' splice site selection.
@en
Interaction of the U1 snRNP wi ...... ects 5' splice site selection.
@nl
prefLabel
Interaction of the U1 snRNP wi ...... ects 5' splice site selection.
@ast
Interaction of the U1 snRNP wi ...... ects 5' splice site selection.
@en
Interaction of the U1 snRNP wi ...... ects 5' splice site selection.
@nl
P2860
P356
P1433
P1476
Interaction of the U1 snRNP wi ...... fects 5' splice site selection
@en
P2093
B Séraphin
P Fabrizio
P2860
P304
P356
10.1101/GAD.13.5.569
P407
P577
1999-03-01T00:00:00Z