Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase.
about
SF1 and SF2 helicases: family mattersA human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group MGenome-wide requirements for resistance to functionally distinct DNA-damaging agents.Functions and regulation of the multitasking FANCM family of DNA motor proteinsYeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination.The MPH1 gene of Saccharomyces cerevisiae functions in Okazaki fragment processing.Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repairComponents of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast.Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae.Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance.Mph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination.Origin and evolution of the RIG-I like RNA helicase gene familyATR activation and replication fork restart are defective in FANCM-deficient cells.Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loopsThe Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiaeReconstitution of DNA repair synthesis in vitro and the role of polymerase and helicase activitiesRegulation of DNA pairing in homologous recombination.Biochemical studies of the Saccharomyces cerevisiae Mph1 helicase on junction-containing DNA structuresFanconi-like crosslink repair in yeast.Mutants defective in Rad1-Rad10-Slx4 exhibit a unique pattern of viability during mating-type switching in Saccharomyces cerevisiae.MTE1 Functions with MPH1 in Double-Strand Break Repair.The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivoImpaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M.Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletionsDosage Mutator Genes in Saccharomyces cerevisiae: A Novel Mutator Mode-of-Action of the Mph1 DNA Helicase.Rad54, the motor of homologous recombination.Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes.Processing of DNA structures via DNA unwinding and branch migration by the S. cerevisiae Mph1 protein.An Overview of the Molecular Mechanisms of Recombinational DNA Repair.Mph1 requires mismatch repair-independent and -dependent functions of MutSalpha to regulate crossover formation during homologous recombination repair.The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair.The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway.Roles of DNA helicases in the mediation and regulation of homologous recombination.Biochemical Activities and Genetic Functions of the Drosophila melanogaster Fancm Helicase in DNA Repair.Avoidance of APOBEC3B-induced mutation by error-free lesion bypassDefects in DNA lesion bypass lead to spontaneous chromosomal rearrangements and increased cell death.Identification of multiple distinct Snf2 subfamilies with conserved structural motifs.Essential domains of Schizosaccharomyces pombe Rad8 required for DNA damage responseGenetic evidence for a role of Saccharomyces cerevisiae Mph1 in recombinational DNA repair under replicative stress.The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair.
P2860
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P2860
Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase.
description
2005 nî lūn-bûn
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2005 թուականի Մարտին հրատարակուած գիտական յօդուած
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2005 թվականի մարտին հրատարակված գիտական հոդված
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2005年の論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年论文
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name
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@ast
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@en
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@nl
type
label
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@ast
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@en
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@nl
prefLabel
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@ast
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@en
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@nl
P2093
P2860
P3181
P356
P1476
Saccharomyces cerevisiae MPH1 ...... codes a 3' to 5' DNA helicase.
@en
P2093
Kirsten Anke Schürer
Patrick Sung
Rohit Prakash
Stephen Van Komen
Wilfried Kramer
P2860
P304
P3181
P356
10.1074/JBC.M413898200
P407
P50
P577
2005-03-04T00:00:00Z