A cryptic protease couples deubiquitination and degradation by the proteasome.
about
The proteasome and the delicate balance between destruction and rescueJAMM: a metalloprotease-like zinc site in the proteasome and signalosomeMPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 functionThe proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break responseRad23 ubiquitin-associated domains (UBA) inhibit 26 S proteasome-catalyzed proteolysis by sequestering lysine 48-linked polyubiquitin chainsCrystal structure of human otubain 2.A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomesRelative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasomeEvidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint controlHuman autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagyhRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37A deubiquitinase negatively regulates retro-translocation of nonubiquitinated substratesA histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulationSem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiaeProteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPasesOtubains: a new family of cysteine proteases in the ubiquitin pathwayStructure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chainsRegulation and cellular roles of ubiquitin-specific deubiquitinating enzymesInhibition of p97-dependent protein degradation by Eeyarestatin IAMSH is an endosome-associated ubiquitin isopeptidaseUse of RNA interference and complementation to study the function of the Drosophila and human 26S proteasome subunit S13Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substratePrediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes.PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexesThe life cycle of the 26S proteasome: from birth, through regulation and function, and onto its deathSubstrate specificity of the ubiquitin and Ubl proteasesRole of Deubiquitinating Enzymes in DNA RepairFine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at workThe 26S proteasome is a multifaceted target for anti-cancer therapiesRegulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genesNuclear Import of Yeast ProteasomesFunctions of the 19S complex in proteasomal degradationThe delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyGraded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome PathwayCrystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutantsUbiquitin docking at the proteasome through a novel pleckstrin-homology domain interactionStructure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13
P2860
Q21092835-AE72110D-5CC9-472C-890C-8481DB813D35Q21092836-F4239CA5-D475-453F-A77D-035C53D38A6BQ21284393-22B013FC-F84F-4EFE-964A-2C099B76B28AQ24297147-21F9EF48-7081-4CBA-96EF-5D507FFF40D6Q24298011-8E2F003C-53CD-4139-A14B-E49B34208859Q24299598-0289487C-7DB6-4036-8A4D-6C099FA2A5CEQ24304237-23A28E99-B622-4B83-AB50-20B8FB74AF2DQ24305134-044BB990-C9C2-45FB-9FB2-1F5FECC1A58AQ24310203-DFEA7422-624F-4AD0-A5C9-6F25080111B2Q24310641-67912099-2DFA-42C9-B8EB-187CE7200D76Q24317325-01EB4EAE-6D43-4F19-BD52-98623C025741Q24320173-410ED7A7-97F3-4E41-9EF7-4142B6460062Q24321826-B0AFF554-03B9-4DF9-AA8E-D5CC094BD1D1Q24337261-6343CCF1-F822-4256-A4BE-8FE3DA24D80AQ24337802-7FC6A172-5895-42B0-8C87-2994BB811EC0Q24338419-BFB1E178-B02D-4F15-8CCF-9524F9E9C0E3Q24522673-5CA00036-312B-4626-A4CA-C605764B56D0Q24535702-FBAADB22-782D-4ABA-9E18-09196EDAEF08Q24537053-602A78BE-2B95-4B61-B835-B40B832DA1F2Q24621713-890B19BE-4FD9-4BFF-9CFD-571DA5ADC0F4Q24645701-34A15F1F-A93F-4588-988C-6DDB13937D06Q24648805-FFF8C35D-D84B-431F-910D-49578E925010Q24676880-C6278C8A-4DFB-4B29-9674-87460DABEF2AQ24681220-CE3C4B56-8587-484F-8464-50CAC72AFBA4Q24683820-49668523-D507-4BD3-83C6-60E32AE1ACA4Q24811581-7B4EB21A-85C5-47DB-BE45-C521127EAFAFQ24815484-038938C3-0FE1-46B5-89C0-4677FFFAD709Q26738549-EB2466AA-B0AF-4928-9120-3D74F5E414EEQ26751372-8CEC2AEC-8761-471A-95D2-1D095D7B70B3Q26773800-26582A33-9B3F-4F6D-A996-4BAF67BE644FQ26781153-B6342079-1827-426B-95C9-E7A2FEB36FAAQ26795764-C4FF1348-CD68-4CFE-BD45-7B752CE3AEA2Q26799208-6B326A6A-B8F7-4A5B-AACD-4A8EF0AA3664Q26799309-089E161D-C955-4B05-8D20-0C84629A2A80Q26996345-5B2E83CD-3F0B-4CC0-A10D-9C60B6000825Q27015793-DCCF46BA-D6B7-430B-8540-01126904FEE3Q27309148-7B3E6503-9A21-4806-94D8-7482F64DE902Q27644658-6E0B49B8-ABF9-4FB6-ABB8-80D32315C26DQ27650666-6CFDF81C-5414-45A6-8163-CCB440C00B14Q27657027-A7A4AAA7-9561-4516-AE2B-493D108B00E0
P2860
A cryptic protease couples deubiquitination and degradation by the proteasome.
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A cryptic protease couples deubiquitination and degradation by the proteasome.
@ast
A cryptic protease couples deubiquitination and degradation by the proteasome.
@en
A cryptic protease couples deubiquitination and degradation by the proteasome.
@nl
type
label
A cryptic protease couples deubiquitination and degradation by the proteasome.
@ast
A cryptic protease couples deubiquitination and degradation by the proteasome.
@en
A cryptic protease couples deubiquitination and degradation by the proteasome.
@nl
prefLabel
A cryptic protease couples deubiquitination and degradation by the proteasome.
@ast
A cryptic protease couples deubiquitination and degradation by the proteasome.
@en
A cryptic protease couples deubiquitination and degradation by the proteasome.
@nl
P2860
P3181
P356
P1433
P1476
A cryptic protease couples deubiquitination and degradation by the proteasome.
@en
P2093
Robert E Cohen
Tingting Yao
P2860
P2888
P3181
P356
10.1038/NATURE01071
P407
P577
2002-09-26T00:00:00Z
P6179
1041564613