Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA
about
The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structuresHuman endonuclease V is a ribonuclease specific for inosine-containing RNADiversity of Endonuclease V: From DNA Repair to RNA EditingThe human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic coreA disease spectrum for ITPA variation: advances in biochemical and clinical researchEnhancing the utility of Proteomics Signature Profiling (PSP) with Pathway Derived Subnets (PDSs), performance analysis and specialised ontologies.Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics.Disruption of de novo purine biosynthesis in Pseudomonas fluorescens Pf0-1 leads to reduced biofilm formation and a reduction in cell size of surface-attached but not planktonic cells.Deoxyinosine repair in nuclear extracts of human cells.High-Frequency Variation of Purine Biosynthesis Genes Is a Mechanism of Success in Campylobacter jejuni.Methylation and expression analyses of Pallister-Killian syndrome reveal partial dosage compensation of tetrasomy 12p and hypomethylation of gene-poor regions on 12p.Increased levels of inosine in a mouse model of inflammationDeoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cellsITPA (inosine triphosphate pyrophosphatase): from surveillance of nucleotide pools to human disease and pharmacogeneticsModulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools.Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates.Preventive DNA repair by sanitizing the cellular (deoxy)nucleoside triphosphate pool.Hypoxanthine-guanine phosphoribosyltransferase and inosine 5'-monophosphate dehydrogenase activities in three mammalian species: aquatic (Mirounga angustirostris), semi-aquatic (Lontra longicaudis annectens) and terrestrial (Sus scrofa).RNAi mediated gene silencing of ITPA using a targeted nanocarrier: Apoptosis induction in SKBR3 cancer cells.Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthine.Insights into the role of endonuclease V in RNA metabolism in Trypanosoma brucei.Recessive ITPA mutations cause an early infantile encephalopathy.Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules.Do variations in the ITPA gene determine the risk of hepatitis C virus relapse?Ultrafast electronic deactivation dynamics of the inosine dimer--a model case for H-bonded purine bases.Computational studies on the energetic properties of polynitroxanthines.Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry.The mesophilic archaeon Methanosarcina acetivorans counteracts uracil in DNA with multiple enzymes: EndoQ, ExoIII, and UDG
P2860
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P2860
Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA
@ast
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA
@en
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA.
@nl
type
label
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA
@ast
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA
@en
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA.
@nl
prefLabel
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA
@ast
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA
@en
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA.
@nl
P2093
P2860
P3181
P356
P1476
Defects in purine nucleotide m ...... hypoxanthine into DNA and RNA
@en
P2093
C Eric Elmquist
Jose L McFaline
Koli Taghizadeh
Matthew R Sullivan
Nicholas E Burgis
Richard P Cunningham
P2860
P304
P3181
P356
10.1073/PNAS.1118455109
P407
P577
2012-02-14T00:00:00Z