Positive regulation in the general amino acid control of Saccharomyces cerevisiae
about
v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomasThe histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acidsThe transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acidsStructure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)Gene overexpression: uses, mechanisms, and interpretationCrystal structure of a super leucine zipper, an extended two-stranded super long coiled coilGuanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae.Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway.eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1.Regulation of the transcription factor Gcn4 by Pho85 cyclin PCL5.Yeast Gcn4p stabilization is initiated by the dissociation of the nuclear Pho85p/Pcl5p complex.Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression.YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed.The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.Sequence-specific initiator elements focus initiation of transcription to distinct sites in the yeast TRP4 promoter.Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational controlGuanine nucleotide exchange factor for eukaryotic translation initiation factor 2 in Saccharomyces cerevisiae: interactions between the essential subunits GCD2, GCD6, and GCD7 and the regulatory subunit GCN3.GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiaeSaccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1.Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake.GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequencesHomologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2.Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation.Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells.Duality in bromodomain-containing protein complexesCDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiaePhylogenetic diversity of stress signalling pathways in fungi.Genetic and molecular analyses of the SUP201 gene: a tRNA(3Arg) nonsense suppressor of yeast cyrl-2Interpathway regulation of the TRP4 gene of yeast.The cross-pathway control gene of Neurospora crassa, cpc-1, encodes a protein similar to GCN4 of yeast and the DNA-binding domain of the oncogene v-jun-encoded proteinSelective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiaeGCD14p, a repressor of GCN4 translation, cooperates with Gcd10p and Lhp1p in the maturation of initiator methionyl-tRNA in Saccharomyces cerevisiae.The role of fnx1, a fission yeast multidrug resistance protein, in the transition of cells to a quiescent G0 state.Identification of Nitrogen Consumption Genetic Variants in Yeast Through QTL Mapping and Bulk Segregant RNA-Seq Analyses.Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availabilitySnf1 promotes phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 by activating Gcn2 and inhibiting phosphatases Glc7 and Sit4.Three GCN4 responsive elements act synergistically as upstream and as TATA-like elements in the yeast TRP4 promoter.SUM1, an apparent positive regulator of the cryptic mating-type loci in Saccharomyces cerevisiae.
P2860
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P248
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P2860
Positive regulation in the general amino acid control of Saccharomyces cerevisiae
description
1983 nî lūn-bûn
@nan
1983 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1983 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
name
Positive regulation in the general amino acid control of Saccharomyces cerevisiae
@ast
Positive regulation in the general amino acid control of Saccharomyces cerevisiae
@en
Positive regulation in the general amino acid control of Saccharomyces cerevisiae.
@nl
type
label
Positive regulation in the general amino acid control of Saccharomyces cerevisiae
@ast
Positive regulation in the general amino acid control of Saccharomyces cerevisiae
@en
Positive regulation in the general amino acid control of Saccharomyces cerevisiae.
@nl
prefLabel
Positive regulation in the general amino acid control of Saccharomyces cerevisiae
@ast
Positive regulation in the general amino acid control of Saccharomyces cerevisiae
@en
Positive regulation in the general amino acid control of Saccharomyces cerevisiae.
@nl
P2860
P3181
P356
P1476
Positive regulation in the general amino acid control of Saccharomyces cerevisiae
@en
P2093
A G Hinnebusch
P2860
P304
P3181
P356
10.1073/PNAS.80.17.5374
P407
P577
1983-09-01T00:00:00Z