A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae
about
Diverse RNA-binding proteins interact with functionally related sets of RNAs, suggesting an extensive regulatory systemFunctional elements in initiation factors 1, 1A, and 2β discriminate against poor AUG context and non-AUG start codonsEnhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan importGuanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae.The TRP4 gene of Saccharomyces cerevisiae: isolation and structural analysis.Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway.Transcriptional-translational regulatory circuit in Saccharomyces cerevisiae which involves the GCN4 transcriptional activator and the GCN2 protein kinase.Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression.TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectorsSequence-specific initiator elements focus initiation of transcription to distinct sites in the yeast TRP4 promoter.Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational controlGCD11, a negative regulator of GCN4 expression, encodes the gamma subunit of eIF-2 in Saccharomyces cerevisiaeGene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2.Structural integrity of {alpha}-helix H12 in translation initiation factor eIF5B is critical for 80S complex stability.Guanine nucleotide exchange factor for eukaryotic translation initiation factor 2 in Saccharomyces cerevisiae: interactions between the essential subunits GCD2, GCD6, and GCD7 and the regulatory subunit GCN3.The Sua5 protein is essential for normal translational regulation in yeast.GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.Complex formation by positive and negative translational regulators of GCN4.The yeast eukaryotic translation initiation factor 2B translation initiation complex interacts with the fatty acid synthesis enzyme YBR159W and endoplasmic reticulum membranesPosttranscriptional control of gene expression in yeast.eIF2γ mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation.Beyond tRNA cleavage: novel essential function for yeast tRNA splicing endonuclease unrelated to tRNA processing.Translation initiation requires cell division cycle 123 (Cdc123) to facilitate biogenesis of the eukaryotic initiation factor 2 (eIF2).GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequencesYeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression.A chemical genomics study identifies Snf1 as a repressor of GCN4 translationCoupled release of eukaryotic translation initiation factors 5B and 1A from 80S ribosomes following subunit joining.RAP1 is required for BAS1/BAS2- and GCN4-dependent transcription of the yeast HIS4 gene.A ribosomal protein is required for translational regulation of GCN4 mRNA. Evidence for involvement of the ribosome in eIF2 recycling.Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation.Regulation of expression of GLT1, the gene encoding glutamate synthase in Saccharomyces cerevisiaeStructural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complexFortuitous convergences: the beginnings of JUNCharacterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation.Evolution of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase-encoding genes in the yeast Saccharomyces cerevisiae.Arginine-specific repression in Saccharomyces cerevisiae: kinetic data on ARG1 and ARG3 mRNA transcription and stability support a transcriptional control mechanism.Interpathway regulation of the TRP4 gene of yeast.Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiaeEvidence for regulation of reinitiation in translational control of GCN4 mRNA.Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability
P2860
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P2860
A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae
description
1985 nî lūn-bûn
@nan
1985 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
name
A hierarchy of trans-acting fa ...... es in Saccharomyces cerevisiae
@ast
A hierarchy of trans-acting fa ...... es in Saccharomyces cerevisiae
@en
A hierarchy of trans-acting fa ...... s in Saccharomyces cerevisiae.
@nl
type
label
A hierarchy of trans-acting fa ...... es in Saccharomyces cerevisiae
@ast
A hierarchy of trans-acting fa ...... es in Saccharomyces cerevisiae
@en
A hierarchy of trans-acting fa ...... s in Saccharomyces cerevisiae.
@nl
prefLabel
A hierarchy of trans-acting fa ...... es in Saccharomyces cerevisiae
@ast
A hierarchy of trans-acting fa ...... es in Saccharomyces cerevisiae
@en
A hierarchy of trans-acting fa ...... s in Saccharomyces cerevisiae.
@nl
P2860
P356
P1476
A hierarchy of trans-acting fa ...... es in Saccharomyces cerevisiae
@en
P2093
A G Hinnebusch
P2860
P304
P356
10.1128/MCB.5.9.2349
P407
P577
1985-09-01T00:00:00Z