Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
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DNA Polymerase θ: A Unique Multifunctional End-Joining MachineDrugging the Cancers Addicted to DNA Repair.Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repairComplex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells.Annealing of Complementary DNA Sequences During Double-Strand Break Repair in Drosophila Is Mediated by the Ortholog of SMARCAL1.Human Cell Assays for Synthesis-Dependent Strand Annealing and Crossing over During Double-Strand Break Repair.Persistent damaged bases in DNA allow mutagenic break repair in Escherichia coli.The control of DNA repair by the cell cycle.Whole-Genome Sequencing of Cytogenetically Balanced Chromosome Translocations Identifies Potentially Pathological Gene Disruptions and Highlights the Importance of Microhomology in the Mechanism of Formation.Dual loss of human POLQ and LIG4 abolishes random integration.Expression and Structural Analyses of Human DNA Polymerase θ (POLQ).Secondary structure forming sequences drive SD-MMEJ repair of DNA double-strand breaks.Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.DNA polymerase beta participates in DNA End-joining.The helicase domain of Polθ counteracts RPA to promote alt-NHEJ.DNA repair factor RAD18 and DNA polymerase Polκ confer tolerance of oncogenic DNA replication stress.Endogenous sequence patterns predispose the repair modes of CRISPR/Cas9-induced DNA double-stranded breaks in Arabidopsis thaliana.Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.Telomere Length Dynamics and the Evolution of Cancer Genome Architecture.How cells ensure correct repair of DNA double-strand breaks.Translesion and Repair DNA Polymerases: Diverse Structure and Mechanism.Repair of DNA double-strand breaks by mammalian alternative end-joining pathways.UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains.FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells.Polymerase θ-helicase efficiently unwinds DNA and RNA-DNA hybridsBRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
P2860
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P2860
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
@en
type
label
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
@en
prefLabel
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
@en
P2093
P2860
P50
P1433
P1476
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
@en
P2093
Gaorav P Gupta
Matthew J Yousefzadeh
Michael P Conlin
Steven A Roberts
Wanjuan Feng
P2860
P304
P356
10.1016/J.MOLCEL.2016.06.020
P577
2016-07-19T00:00:00Z