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Structure of a Highly Active Cephalopod S-crystallin Mutant: New Molecular Evidence for Evolution from an Active Enzyme into Lens-Refractive ProteinAggregate aufgelöstPharmacological chaperone for α-crystallin partially restores transparency in cataract modelsCataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH.Transcriptome of the GSH-Depleted Lens Reveals Changes in Detoxification and EMT Signaling Genes, Transport Systems, and Lipid HomeostasisMutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts.A Common Ancestral Mutation in CRYBB3 Identified in Multiple Consanguineous Families with Congenital Cataracts.Case report of homozygous deletion involving the first coding exons of GCNT2 isoforms A and B and part of the upstream region of TFAP2A in congenital cataractMutation in LIM2 Is Responsible for Autosomal Recessive Congenital CataractsDeletion at the GCNT2 Locus Causes Autosomal Recessive Congenital CataractsPolymorphism rs7278468 is associated with Age-related cataract through decreasing transcriptional activity of the CRYAA promoter.Cataract-causing mutation S228P promotes βB1-crystallin aggregation and degradation by separating two interacting loops in C-terminal domainLens: Management of Cataract Surgery, Cataract Prevention, and Floppy Iris Syndrome.Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases.Systems biology of lens development: A paradigm for disease gene discovery in the eye.Small molecules, both dietary and endogenous, influence the onset of lens cataracts.Effect of lanosterol on human cataract nucleus.Mutations and mechanisms in congenital and age-related cataracts.Novel phenotypes and loci identified through clinical genomics approaches to pediatric cataract.Inherited Congenital Cataract: A Guide to Suspect the Genetic Etiology in the Cataract Genesis.Pharmacological approaches to restoring lens transparency: Real world applications.Paradigm shifts, peregrinations and pixies in ophthalmology.An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin.Identification of a novel GJA3 mutation in a large Chinese family with congenital cataract using targeted exome sequencing.Aggregation of Trp > Glu point mutants of human gamma-D crystallin provides a model for hereditary or UV-induced cataract.Comment to: Effect of lanosterol on human nuclei.Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium.A glimpse into this issue.Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.Public impact, prevention, and treatment of cataracts.Whales, lifespan, phospholipids, and cataracts.The 100 most influential papers about cataract surgery: a bibliometric analysis.Light-focusing human micro-lenses generated from pluripotent stem cells model lens development and drug-induced cataract in vitro.Ionizing radiation sensitivity of the ocular lens and its dose rate dependence.Effect of Green Tea Polyphenol Epigallocatechin-3-gallate on the Aggregation of αA(66-80) Peptide, a Major Fragment of αA-crystallin Involved in Cataract Development.Amyloid β-Sheet Secondary Structure Identified in UV-Induced Cataracts of Porcine Lenses using 2D IR Spectroscopy.Functional SNP in 3'-UTR MicroRNA-Binding Site of ZNF350 Confers Risk for Age-Related Cataract.Rosmarinic Acid Restores Complete Transparency of Sonicated Human Cataract Ex Vivo and Delays Cataract Formation In Vivo.Sterol Metabolism and Transport in Atherosclerosis and CancerErratum: Corrigendum: Lanosterol reverses protein aggregation in cataracts
P2860
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P2860
description
2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2015
@ast
scientific journal article
@en
vedecký článok (publikovaný 2015/07/30)
@sk
vědecký článek publikovaný v roce 2015
@cs
wetenschappelijk artikel (gepubliceerd op 2015/07/30)
@nl
наукова стаття, опублікована в липні 2015
@uk
مقالة علمية (نشرت في 30-7-2015)
@ar
name
Lanosterol reverses protein aggregation in cataracts
@ast
Lanosterol reverses protein aggregation in cataracts
@en
Lanosterol reverses protein aggregation in cataracts
@nl
type
label
Lanosterol reverses protein aggregation in cataracts
@ast
Lanosterol reverses protein aggregation in cataracts
@en
Lanosterol reverses protein aggregation in cataracts
@nl
prefLabel
Lanosterol reverses protein aggregation in cataracts
@ast
Lanosterol reverses protein aggregation in cataracts
@en
Lanosterol reverses protein aggregation in cataracts
@nl
P2093
P50
P921
P3181
P356
P1433
P1476
Lanosterol reverses protein aggregation in cataracts
@en
P2093
Austin Qiu
Christopher Chung
Daniel Chen
David Granet
Frances Wu
Guiqun Cao
P2888
P304
P3181
P356
10.1038/NATURE14650
P407
P577
2015-07-30T00:00:00Z
P5875
P6179
1048809680