Functional requirement of p23 and Hsp90 in telomerase complexes
about
Human telomerase contains two cooperating telomerase RNA molecules.Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivoInteraction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradationChaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperonesDifferential regulation of telomerase activity by six telomerase subunitsProteostatic control of telomerase function through TRiC-mediated folding of TCAB1Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assemblyAnalysis of the structure of human telomerase RNA in vivoHuman telomerase and its regulationMinimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitroIdentification of two RNA-binding proteins associated with human telomerase RNAPolymerization defects within human telomerase are distinct from telomerase RNA and TEP1 bindingMapping of the gene for the human telomerase reverse transcriptase, hTERT, to chromosome 5p15.33 by fluorescence in situ hybridizationHepatitis B virus replicationHigh levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistanceBRCA1 inhibition of telomerase activity in cultured cellsHistone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradationMechanisms of Hsp90 regulationTelomere- and Telomerase-Associated Proteins and Their Functions in the Plant CellVariations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancerMolecular regulation of telomerase activity in agingStructure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1Intracellular trafficking of yeast telomerase components.The hsp90 molecular chaperone modulates multiple telomerase activities.HSP90 controls SIR2 mediated gene silencingThe p23 molecular chaperone promotes functional telomerase complexes through DNA dissociationThe yeast Hsp110 family member, Sse1, is an Hsp90 cochaperone.Telomerase Regulation from Beginning to the EndUnderstanding the role of heat shock protein isoforms in male fertility, aging and apoptosisHuman Ku70/80 associates physically with telomerase through interaction with hTERTTelomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivoThe Telomerase/vault-associated protein TEP1 is required for vault RNA stability and its association with the vault particleVaults and telomerase share a common subunit, TEP1Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylationDirect activation of HSP90A transcription by c-Myc contributes to c-Myc-induced transformationDNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptaseNucleolin interacts with telomeraseGeldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperonesHuman telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivoRole of Smad3 in the regulation of rat telomerase reverse transcriptase by TGFbeta
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P2860
Functional requirement of p23 and Hsp90 in telomerase complexes
description
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
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im April 1999 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 1999/04/01)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/04/01)
@nl
наукова стаття, опублікована у квітні 1999
@uk
научни чланак (објављен 1999/04/01)
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name
Functional requirement of p23 and Hsp90 in telomerase complexes
@ast
Functional requirement of p23 and Hsp90 in telomerase complexes
@en
Functional requirement of p23 and Hsp90 in telomerase complexes
@nl
type
label
Functional requirement of p23 and Hsp90 in telomerase complexes
@ast
Functional requirement of p23 and Hsp90 in telomerase complexes
@en
Functional requirement of p23 and Hsp90 in telomerase complexes
@nl
prefLabel
Functional requirement of p23 and Hsp90 in telomerase complexes
@ast
Functional requirement of p23 and Hsp90 in telomerase complexes
@en
Functional requirement of p23 and Hsp90 in telomerase complexes
@nl
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P2860
P921
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P1476
Functional requirement of p23 and Hsp90 in telomerase complexes
@en
P2093
D L Aisner
J B Trager
M Ouellette
V M Tesmer
W E Wright
P2860
P304
P3181
P356
10.1101/GAD.13.7.817
P577
1999-04-01T00:00:00Z