7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
about
Matrin 3 binds and stabilizes mRNAThe RNA degradation pathway regulates the function of GAS5 a non-coding RNA in mammalian cellsThe mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SKInhibition of Tat activity by the HEXIM1 proteinCompensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcriptionHEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SKHuman transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complexIdentification of HEXIM1 as a positive regulator of p53Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genesA human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat.HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor bRNA helicase DDX21 coordinates transcription and ribosomal RNA processingAcetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcriptionThe La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genesBrd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause releaseAcetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cellsThe human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcriptionSystematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzymeThe structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylationPhosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongationA Cajal body-specific pseudouridylation guide RNA is composed of two box H/ACA snoRNA-like domains.The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivatorThe FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNPA human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFbBinding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitorThe Drosophila 7SK snRNP and the essential role of dHEXIM in developmentRole of the C-terminal domain of RNA polymerase II in U2 snRNA transcription and 3' processingRegulatory long non-coding RNAs and neuronal disorders7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcriptionStructured non-coding RNAs and the RNP RenaissanceSuberoylanilide hydroxamic acid reactivates HIV from latently infected cellsLARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associatedTLS inhibits RNA polymerase III transcriptionRecruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML proteinRegulation of P-TEFb elongation complex activity by CDK9 acetylationMAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent mannerDevelopmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcriptionNONCODE: an integrated knowledge database of non-coding RNAsA new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongationOligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb
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P2860
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
description
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2001
@ast
scientific journal article
@en
vedecký článok (publikovaný 2001/11/15)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/11/15)
@nl
наукова стаття, опублікована в листопаді 2001
@uk
مقالة علمية (نشرت في 15-11-2001)
@ar
name
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@ast
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@en
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@nl
type
label
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@ast
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@en
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@nl
prefLabel
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@ast
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@en
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/35104581
P407
P577
2001-11-01T00:00:00Z
P6179
1003425486