Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stressSestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1Advances in Autophagy Regulatory MechanismsSestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose TissueAutophagy in malignant transformation and cancer progressionRole of p62/SQSTM1 in liver physiology and pathogenesisThe role of tumor suppressor p53 in the antioxidant defense and metabolismp62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogrammingJanus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domainsHepatoprotective role of Sestrin2 against chronic ER stressSestrins inhibit mTORC1 kinase activation through the GATOR complexSestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signalingFlesh quality loss in response to dietary isoleucine deficiency and excess in fish: a link to impaired Nrf2-dependent antioxidant defense in muscleOxidative stress, redox signaling, and autophagy: cell death versus survivalOxidative stress and autophagy: the clash between damage and metabolic needsKaposi's sarcoma-associated herpesvirus induces Nrf2 activation in latently infected endothelial cells through SQSTM1 phosphorylation and interaction with polyubiquitinated Keap1Differential Response of Human Embryonic Stem and Somatic Cells to Non-Cytotoxic Hydrogen Peroxide Exposure: An Attempt to Model In Vitro the Effects of Oxidative Stress on the Early Embryop62 links autophagy and Nrf2 signalingMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseSestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signalingPhysical and Flavor Characteristics, Fatty Acid Profile, Antioxidant Status and Nrf2-Dependent Antioxidant Enzyme Gene Expression Changes in Young Grass Carp (Ctenopharyngodon idella) Fillets Fed Dietary ValineModulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseasesSesn2 gene ablation enhances susceptibility to gentamicin-induced hair cell death via modulation of AMPK/mTOR signaling.The Keap1-Nrf2 pathway: promising therapeutic target to counteract ROS-mediated damage in cancers and neurodegenerative diseases.Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species.The inhibitory effect of ethanol on Sestrin3 in the pathogenesis of ethanol-induced liver injurySelenium suppresses leukemia through the action of endogenous eicosanoids.Sestrins orchestrate cellular metabolism to attenuate aging.Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells.Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissuesUpregulation of Sestrin2 expression protects against macrophage apoptosis induced by oxidized low-density lipoprotein.Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.The potential of sestrins as therapeutic targets for diabetes.Stability of HIB-Cul3 E3 ligase adaptor HIB Is Regulated by Self-degradation and Availability of Its Substrates.Kelch-Like Protein 2 Mediates Angiotensin II-With No Lysine 3 Signaling in the Regulation of Vascular Tonus.Prediction and Validation of Transcription Factors Modulating the Expression of Sestrin3 Gene Using an Integrated Computational and Experimental Approach.The Expression of the Endogenous mTORC1 Inhibitor Sestrin 2 Is Induced by UVB and Balanced with the Expression Level of Sestrin 1.Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death.Oxidative stress and autophagy: crucial modulators of kidney injury
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P2860
Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage
description
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2013
@ast
im Januar 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/01/08)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/01/08)
@nl
наукова стаття, опублікована в січні 2013
@uk
مقالة علمية (نشرت في 8-1-2013)
@ar
name
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@ast
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@en
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@nl
type
label
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@ast
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@en
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@nl
prefLabel
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@ast
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@en
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@nl
P2093
P921
P3181
P1433
P1476
Sestrins activate Nrf2 by prom ...... prevent oxidative liver damage
@en
P2093
Dongmin Kang
Hye Eun Lee
Jung Mi Lim
Se Kyoung Lee
Su Haeng Sung
Sue Goo Rhee
Sue Young Oh
P3181
P356
10.1016/J.CMET.2012.12.002
P577
2012-12-27T00:00:00Z