about
Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structureComparative active-site mutation study of human and Caenorhabditis elegans thymidine kinase 1N3-substituted thymidine bioconjugates for cancer therapy and imagingStructural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate bindingFunctional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase. Investigations of the putative catalytic glutamate-arginine pair and of residues responsible for substrate specificityQuaternary Structure Change as a Mechanism for the Regulation of Thymidine Kinase 1-Like EnzymesStructural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinaseCell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma bruceiFunctional diversification of the RING finger and other binuclear treble clef domains in prokaryotes and the early evolution of the ubiquitin systemStructural and Kinetic Characterization of Thymidine Kinase from Leishmania majorStructure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug designMapping protein interactions between Dengue virus and its human and insect hosts.Synthesis of N3-substituted carboranyl thymidine bioconjugates and their evaluation as substrates of recombinant human thymidine kinase 1.A Bioorthogonal Chemical Reporter of Viral Infection.New Variants of Tomato Thymidine Kinase 1 Selected for Increased Sensitivity of E. coli KY895 towards AzidothymidineComputational molecular biology approaches to ligand-target interactions.Antiviral Activity of 4'-thioIDU and Thymidine Analogs against OrthopoxvirusesExpression of tomato thymidine kinase 1 by means of the baculovirus expression vector system.Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration.thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADPSynthesis, anti-HIV activity studies, and in silico rationalization of cyclobutane-fused nucleosides.
P2860
Q24301636-D1BE0825-9F5F-46F7-9379-E5FFBFE7845DQ24306646-8E12CD8B-A4FC-442F-90BD-39EC16BCCD3BQ26827126-31F2ED7F-FCA2-4CD7-862B-7162DC546793Q27643761-7DEFE3E4-50A6-42D9-A952-DDEBAD025D81Q27643825-A5116E44-1232-45E8-B621-EC0F5268962DQ27649280-95BAC49A-E141-49A8-9A28-FE90107D28E1Q27650210-E61FD209-82FE-4E2C-B0B1-F9F9EA50B0C2Q27720126-5B00D18D-9289-40B0-AA09-F8488988746DQ28236887-300A6763-CD97-4BBF-AAB1-B363C847041DQ28547297-8B895EB0-C1BB-49BE-A532-E3578844147BQ33261402-51B66C3F-2CB6-406A-B392-C9A0A406BB57Q33831759-04FEBF6F-0773-4004-930E-9412AFDB7407Q34322534-5E163C35-9124-475E-BF73-FD3A0A8E3A16Q34476370-0B078B2A-0053-44A1-900C-A8DBF1D5F7F3Q34480167-263AEAD4-A595-4489-80FA-20EC4AE442C1Q37684817-EBC6006E-DE7B-418C-9B9F-F3678D301035Q38615818-27F4972D-E30E-47EB-BBEA-AEC53D5BCABBQ40446843-5020E76F-2F93-4344-8570-487015F44BF6Q46195659-18015855-C40D-4741-B3EB-24442069FF1CQ50294623-E0872D31-B017-4CC6-B8B7-4881DB4D21D6Q54517253-E2A57204-877A-49EF-BFB3-4D421F9F1CE2
P2860
description
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Februar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/02/28)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/02/28)
@nl
наукова стаття, опублікована в лютому 2005
@uk
مقالة علمية (نشرت في 28-2-2005)
@ar
name
Structure of a type II thymidine kinase with bound dTTP
@ast
Structure of a type II thymidine kinase with bound dTTP
@en
Structure of a type II thymidine kinase with bound dTTP
@nl
type
label
Structure of a type II thymidine kinase with bound dTTP
@ast
Structure of a type II thymidine kinase with bound dTTP
@en
Structure of a type II thymidine kinase with bound dTTP
@nl
prefLabel
Structure of a type II thymidine kinase with bound dTTP
@ast
Structure of a type II thymidine kinase with bound dTTP
@en
Structure of a type II thymidine kinase with bound dTTP
@nl
P2093
P2860
P1433
P1476
Structure of a type II thymidine kinase with bound dTTP
@en
P2093
Daniel P Kloer
Georg E Schulz
Leonardo Scapozza
Markus S Birringer
Michael T Claus
P2860
P304
P356
10.1016/J.FEBSLET.2005.01.034
P407
P50
P577
2005-02-01T00:00:00Z