Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism
about
Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowthConstitutive activation of the Wnt canonical pathway in mantle cell lymphomaMutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathwaysPlanar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytesDeubiquitination of Dishevelled by Usp14 is required for Wnt signalingIdentification of a novel Wnt5a-CK1ɛ-Dvl2-Plk1-mediated primary cilia disassembly pathwayItch is required for lateral line development in zebrafishThe importance of Wnt signalling for neurodegeneration in Parkinson's diseaseWnt2 regulates progenitor proliferation in the developing ventral midbrainTiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neuronsNon-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer CellsHeterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformationInteractions between Casein kinase Iepsilon (CKIepsilon) and two substrates from disparate signaling pathways reveal mechanisms for substrate-kinase specificityWnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivoSFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cellsThe extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivoDishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signalingReceptor tyrosine kinase gene expression profiles of Ewing sarcomas reveal ROR1 as a potential therapeutic target in metastatic disease.Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerizationAsymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway.Intramucosal distribution of WNT signaling components in human esophagus.Vang-like protein 2 and Rac1 interact to regulate adherens junctions.beta-Arrestins - scaffolds and signalling elements essential for WNT/Frizzled signalling pathways?Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration.Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases.Mutations in Frizzled 6 cause isolated autosomal-recessive nail dysplasia.Regulation of ciliary motility: conserved protein kinases and phosphatases are targeted and anchored in the ciliary axonemeERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane associationNMDA receptor activation stimulates transcription-independent rapid wnt5a protein synthesis via the MAPK signaling pathwayBeta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesisSuperoxide Dismutase 1 In Vivo Ameliorates Maternal Diabetes Mellitus-Induced Apoptosis and Heart Defects Through Restoration of Impaired Wnt Signaling.The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein.Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic LeukemiaAssembly of Dishevelled 3-based supermolecular complexes via phosphorylation and Axin.High casein kinase 1 epsilon levels are correlated with better prognosis in subsets of patients with breast cancer.Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.Wnt-5a-CKI{alpha} signaling promotes {beta}-catenin/E-cadherin complex formation and intercellular adhesion in human breast epithelial cells.
P2860
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
P248
Q24297657-7FD0D16B-D53C-429F-A383-C010AE1698E4Q24312127-FEE53674-718C-42F3-921C-F422C1A50368Q24316917-EF7DBED7-9714-4929-95D3-DE90CA694D6AQ24318698-F2477A27-A885-40C8-8526-12C38407551AQ24318750-241B73FB-FEF4-4F1D-B751-8399DD83365DQ24323675-53009EBE-5AC8-4E48-BEA2-509EC6ED9B7EQ27332234-174E0BE4-768F-4BE0-A396-31D51A4739D5Q28115237-047E34A1-12FD-48FE-9799-0D1AB7C053DCQ28116566-B9DE7200-D284-45D3-BB47-BA73CBB81ED4Q28116790-9B40E09F-0142-4A05-AC31-B98B5F530323Q28269801-35C53942-09E7-4A7A-B297-5BF3C146C0D2Q28389097-6C0694F7-ED76-47FE-B26D-48BCD5E976BEQ28474981-E3B9372F-F603-4C46-840E-D1A8DAA76E88Q28513819-CD23E742-F12E-4E1F-B470-91264123E5BEQ28585649-A4ED92F4-5085-47F6-BCEB-4A32F30705D6Q28588070-6043D177-1C72-4C83-9884-24175A3104C7Q28594872-6D6A0B4A-7C38-4B20-B58C-EC5A980B8631Q30315828-5954558B-8D79-49AD-B817-113D21A4C065Q30495286-DA0FCF46-0629-47B0-AB8E-72F8EDC9D8D6Q30619502-9F310C94-7F4F-44F5-B967-79DE1FF890EEQ33421205-007C5301-C867-402D-88DE-97B94D2AD8A4Q33629181-96C30315-9DFE-459B-A8B1-DF8A12EEE96CQ33730604-E9575DCF-BEFF-4125-8BDB-19E098872E0EQ34048070-D2DE02D8-31D7-43BA-9DCE-59768BB85D2CQ34141145-94B6404D-45C1-4A0A-9995-DBEC7E10D334Q34289087-7C04AA04-CB66-4D7A-A207-6D618DDC3674Q34695767-82A7E7C3-3F05-42D9-9F7D-EE36EA57286EQ35039924-B51ACB00-5CF1-4EDF-9661-0AF5AB3A4641Q35043160-D7943C8E-3007-475A-A071-10207284094EQ35214896-3EFDB25A-0617-48B1-B569-38B41A1DBD6EQ35779777-81A26365-8D1D-4736-ADE4-39697197D67FQ35800324-8E31D07F-0363-4A1F-B44B-9F8B005B7F36Q35837144-CEB641E9-0DD5-47DD-B19E-11185F2608A4Q36199977-90185BA0-75AF-4E0A-A39E-37373FF3B2DBQ36277250-45BC8056-7BDE-4606-B8C8-4CBD97C1DE7CQ36471596-5BABD56F-DD16-4EA6-A2B1-71C582B8A55AQ36523966-77A2C60A-A752-4230-9045-91D783DEBB9EQ36557595-587DC6E2-EF18-48BA-9BAC-53201B41EA8AQ36725106-7F515BAD-0968-4AFD-9280-D219D7D8DEC3Q37155506-785EEE02-34B5-4CD8-B749-44C7E0454CB4
P2860
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism
description
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Februar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/02/15)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/02/15)
@nl
наукова стаття, опублікована в лютому 2007
@uk
مقالة علمية (نشرت في 15-2-2007)
@ar
name
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@ast
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@en
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@nl
type
label
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@ast
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@en
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@nl
prefLabel
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@ast
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@en
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@nl
P50
P921
P356
P1476
Wnt-5a induces Dishevelled pho ...... via a CK1-dependent mechanism
@en
P2093
Nina Rawal
P304
P356
10.1242/JCS.03368
P407
P577
2007-01-23T00:00:00Z