Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
about
The ubiquitin ligase RNF220 enhances canonical Wnt signaling through USP7-mediated deubiquitination of β-cateninDeubiquitinating enzymes as oncotargetsPeeling away the layers of ubiquitin signaling complexities with synthetic ubiquitin-protein conjugates.Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compoundsIn vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryosUbiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junctionAn optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes.Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer developmentUbiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerizationMutations in DVL1 cause an osteosclerotic form of Robinow syndrome.Facilitated Tau Degradation by USP14 Aptamers via Enhanced Proteasome Activity.Deubiquitinases in cancer.USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling.Regulation of Wnt/β-catenin signaling by posttranslational modificationsThe cellular story of dishevelleds.DUBs, the regulation of cell identity and disease.Downregulation of ubiquitin-specific protease 14 (USP14) inhibits breast cancer cell proliferation and metastasis, but promotes apoptosis.Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled.Pharmacological folding chaperones act as allosteric ligands of Frizzled4.Ubiquitin-specific protease 14 regulates LPS-induced inflammation by increasing ERK1/2 phosphorylation and NF-κB activation.An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway.Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents.Regulation of the ubiquitylation and deubiquitylation of CREB-binding protein modulates histone acetylation and lung inflammation.Meddling with Fate: The Proteasomal Deubiquitinating Enzymes.Deubiquitylating enzymes and drug discovery: emerging opportunities.The function of endocytosis in Wnt signaling.Ubiquitin-Specific Protease 14 Negatively Regulates Toll-Like Receptor 4-Mediated Signaling and Autophagy Induction by Inhibiting Ubiquitination of TAK1-Binding Protein 2 and Beclin 1.Ubiquitination in Scleroderma Fibrosis and Its TreatmentDeubiquitinating Enzymes Related to Autophagy: New Therapeutic Opportunities?Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN
P2860
Q24304871-23F78201-561B-4B76-A4F5-23C0D6B00D12Q27026189-ED29480F-2E39-4B7A-B4EE-A72170319BF3Q27693783-AEE86D47-0009-4278-827A-454AC82C4834Q27935947-316ABE74-DACE-42BB-A57C-4EDDAD39A3BFQ28082497-7DC627DF-1A58-4BF7-B120-A86AB3905109Q30586942-84C98233-B88F-4CD3-B884-BB4985C19779Q30646859-3E2B7BB0-98BB-41E4-A6C9-356AC0B66E2AQ34063163-741D905B-920C-4B12-A400-7CD30AB2B345Q34471536-D4638064-86E7-4569-ABAC-ABBEF415DC8CQ35579401-376D7A49-B9A7-4AE8-B2EF-940201DFD66BQ35589023-2531713E-E343-493D-B013-CAFD151196EEQ35682065-6DEC6C0D-3845-45F3-AFEC-DA7325A651E2Q35955141-B874A08A-4451-4D8E-A0A6-3055CB14E1EDQ37212992-2DCCC4E5-9E07-468F-874A-232D73B06C55Q37642658-8424BF20-E863-46AF-9C1A-4727D5259E7EQ38193259-FCCCE5A7-C6CD-4F9E-8A4B-3B66D19CD318Q38264039-F4F30CD6-5622-4574-9F95-8295B876BA43Q38336126-36F00440-EC4B-4A60-808B-6BCA28B20CD6Q38808345-CBD84688-8B1C-4F3B-917E-885C7033A0D3Q38809243-9BEF18A3-190B-4820-AB34-280A043C1763Q38902274-6A8F8966-65BA-4BA1-91EF-453FA8D2D3A2Q40269812-7AE5557F-9FF6-4E26-84A1-7C21C7400D4FQ46916073-B2649A74-38DA-426A-9EA4-3254E9F6C6E2Q47069565-4C0C220B-F427-4181-9505-DB05BEEADE07Q47098444-ADDA2165-C649-424C-A4B6-731B72FAB8C0Q47285696-F1531253-0B3B-4311-8A1D-66300630B72EQ47292178-EF4FB84F-1B2B-4BFB-946D-07496372E195Q48265884-6C616D25-9D8C-466D-9D42-B30B88C915F1Q48341993-5AB34FA5-CBC9-4A8E-8038-F2C79EDFA101Q49522804-9FB7F983-CE76-4044-BDB0-F5F554056345Q58606339-6B9181B3-BB6F-4B67-9294-04DC7D28A6D7Q58766259-24A3AA37-2DFA-410E-953D-08D1579C563FQ59133408-8A67A0B3-28F1-44F1-9413-F679EE2D4923
P2860
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@ast
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@en
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@en-gb
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@nl
type
label
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@ast
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@en
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@en-gb
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@nl
prefLabel
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@ast
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@en
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@en-gb
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@nl
P2093
P2860
P356
P1433
P1476
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
@en
P2093
P2860
P2888
P356
10.1038/ONCSIS.2013.28
P407
P577
2013-08-19T00:00:00Z
P5875
P6179
1018822920