The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome - Wikidata - wikimedia - TriplyDB

The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome

The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome

http://www.wikidata.org/entity/Q28137728

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Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction Notch signaling is essential for ventricular chamber development Jagged1 (JAG1) mutations in patients with tetralogy of Fallot or pulmonic stenosis Slug is a direct Notch target required for initiation of cardiac cushion cellularization JAGGED1 expression in human embryos: correlation with the Alagille syndrome phenotype Coordinating tissue interactions: Notch signaling in cardiac development and disease Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome Notch1 signaling stimulates proliferation of immature cardiomyocytes Jagged1 (JAG1): Structure, expression, and disease associations Discovery of novel determinants of endothelial lineage using chimeric heterokaryons.Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cells Gene expression in pediatric heart disease with emphasis on conotruncal defects.Embryonic Development of the Bicuspid Aortic Valve.Jagged1 mutations in alagille syndrome.Facial features in Alagille syndrome: specific or cholestasis facies?Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects Loss of Gata5 in mice leads to bicuspid aortic valve.Gene Transcriptional and Metabolic Profile Changes in Mimetic Aging Mice Induced by D-Galactose The role of notch in modeling and maintaining the vasculature.Cartilage, SOX9 and Notch signals in chondrogenesis.Embryonic cardiac chamber maturation: Trabeculation, conduction, and cardiomyocyte proliferation.Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein Familial deafness, congenital heart defects, and posterior embryotoxon caused by cysteine substitution in the first epidermal-growth-factor-like domain of jagged 1.Notch signaling in cardiac valve development and disease.Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development.Developmental and extracellular matrix-remodeling processes in rosiglitazone-exposed neonatal rat cardiomyocytes.A Serrate-expressing signaling center controls Drosophila hematopoiesis.Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jkappa-dependent pathway.Ectopic Noggin in a Population of Nfatc1 Lineage Endocardial Progenitors Induces Embryonic Lethality.Notch1 and Jagged1 expression by the developing pulmonary vasculature.A novel reporter allele for monitoring Dll4 expression within the embryonic and adult mouse.Aortic coarctation and carotid artery aneurysm in a patient with Hardikar syndrome: Cardiovascular implications for affected individuals.JAG1Mutation in a patient with deletion 22q11.2 syndrome and tetralogy of Fallot

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P2860

The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome

http://www.wikidata.org/entity/Q28137728

description

1999 nî lūn-bûn

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1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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Human Molecular Genetics

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The expression of Jagged1 in t ...... r disease in Alagille syndrome

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P2093

D A Piccoli

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H S Baldwin

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J Morabito

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K M Loomes

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L A Underkoffler

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N B Spinner

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R J Oakey

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S Gottlieb

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P2860

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development

An antisense oligonucleotide to the notch ligand jagged enhances fibroblast growth factor-induced angiogenesis in vitro

Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

Jagged: a mammalian ligand that activates Notch1

Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

Notch signaling

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10.1093/HMG/8.13.2443

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13

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1999-12-01T00:00:00Z

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10556292

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P921

cardiovascular disease