Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: implications for different functions?
about
Phospholipid scramblase 1 potentiates the antiviral activity of interferonGolgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactorHuman guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitisDeterminants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control itCytokine-related genes identified from the RIKEN full-length mouse cDNA data setAnalyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies.Allergen challenge induces Ifng dependent GTPases in the lungs as part of a Th1 transcriptome response in a murine model of allergic asthma.Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes.The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein.Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes.IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens.Emerging themes in IFN-gamma-induced macrophage immunity by the p47 and p65 GTPase families.Autophagy restricts Chlamydia trachomatis growth in human macrophages via IFNG-inducible guanylate binding proteins.Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease.The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase.The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.Mechanisms and functions of guanylate-binding proteins and related interferon-inducible GTPases: roles in intracellular lysis of pathogens.Guanylate-binding protein 2 regulates Drp1-mediated mitochondrial fission to suppress breast cancer cell invasion.
P2860
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P2860
Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: implications for different functions?
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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Different subcellular localiza ...... tions for different functions?
@ast
Different subcellular localiza ...... tions for different functions?
@en
Different subcellular localiza ...... tions for different functions?
@nl
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label
Different subcellular localiza ...... tions for different functions?
@ast
Different subcellular localiza ...... tions for different functions?
@en
Different subcellular localiza ...... tions for different functions?
@nl
prefLabel
Different subcellular localiza ...... tions for different functions?
@ast
Different subcellular localiza ...... tions for different functions?
@en
Different subcellular localiza ...... tions for different functions?
@nl
P2093
P1476
Different subcellular localiza ...... tions for different functions?
@en
P2093
D J Vestal
V Y Gorbacheva
P304
P356
10.1089/10799900050198435
P407
P577
2000-11-01T00:00:00Z