Defective NK cell activation in X-linked lymphoproliferative disease
about
The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activationStructural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cellsResponses to Microbial Challenges by SLAMF ReceptorsFine specificity and molecular competition in SLAM family receptor signallingHigh expression of CD244 and SAP regulated CD8 T cell responses of patients with HTLV-I associated neurologic diseaseGenetic characterisation of spontaneous ankylosing arthropathy with unique inheritance from Fas-deficient strains of miceTonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma.TGF-β1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistenceMolecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors.Recognition of tumors by the innate immune system and natural killer cells.An Epstein-Barr virus encoded inhibitor of Colony Stimulating Factor-1 signaling is an important determinant for acute and persistent EBV infection.CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation.Exploiting the interplay between innate and adaptive immunity to improve immunotherapeutic strategies for Epstein-Barr-virus-driven disordersSLAM Family Receptors Regulate Immunity with and without SAP-related AdaptorsX-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease.Microenvironment abnormalities and lymphomagenesis: Immunological aspects.Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAPNatural killer cell inhibitory receptors block actin cytoskeleton-dependent recruitment of 2B4 (CD244) to lipid rafts.2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells.Interleukin-21 overexpression dominates T cell response to Epstein-Barr virus in a fatal case of X-linked lymphoproliferative syndrome type 1Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP).2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells.Differential requirement for the SAP-Fyn interaction during NK T cell development and function.The switch from latent to productive infection in epstein-barr virus-infected B cells is associated with sensitization to NK cell killing.Lymphoma and cerebral vasculitis in association with X-linked lymphoproliferative disease.Protein kinase C is involved in 2B4 (CD244)-mediated cytotoxicity and AP-1 activation in natural killer cells.Phosphoinositide-3-Kinase Signaling in Human Natural Killer Cells: New Insights from Primary Immunodeficiency.
P2860
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P2860
Defective NK cell activation in X-linked lymphoproliferative disease
description
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Oktober 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: October 2000)
@en
vedecký článok (publikovaný 2000/10/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/10/01)
@nl
наукова стаття, опублікована в жовтні 2000
@uk
مقالة علمية (نشرت في أكتوبر 2000)
@ar
name
Defective NK cell activation in X-linked lymphoproliferative disease
@ast
Defective NK cell activation in X-linked lymphoproliferative disease
@en
Defective NK cell activation in X-linked lymphoproliferative disease
@nl
type
label
Defective NK cell activation in X-linked lymphoproliferative disease
@ast
Defective NK cell activation in X-linked lymphoproliferative disease
@en
Defective NK cell activation in X-linked lymphoproliferative disease
@nl
prefLabel
Defective NK cell activation in X-linked lymphoproliferative disease
@ast
Defective NK cell activation in X-linked lymphoproliferative disease
@en
Defective NK cell activation in X-linked lymphoproliferative disease
@nl
P2093
P1476
Defective NK cell activation in X-linked lymphoproliferative disease
@en
P2093
P304
P407
P577
2000-10-01T00:00:00Z