SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
about
Principles of interleukin (IL)-6-type cytokine signalling and its regulationInterleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signallingPlacental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3A Stat3-interacting protein (StIP1) regulates cytokine signal transductionc-Cbl-dependent monoubiquitination and lysosomal degradation of gp130Cholinergic agonists regulate JAK2/STAT3 signaling to suppress endothelial cell activationgp130 cytokine signaling in the pituitary gland: a paradigm for cytokine-neuro-endocrine pathwaysJoint disease caused by defective gp130-mediated STAT signaling.The biology and mechanism of action of suppressor of cytokine signaling 3The role of suppressors of cytokine signalling in human neoplasmsActivation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular TransformationLeukemia inhibitory factor (LIF)CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha componentSHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130Function and molecular modeling of the interaction between human interleukin 6 and its HNK-1 oligosaccharide ligandsA new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptorSuppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signalingNegative cross-talk between interleukin-3 and interleukin-11 is mediated by suppressor of cytokine signalling-3 (SOCS-3)A completely foreign receptor can mediate an interferon-gamma-like response.Expression of suppressors of cytokine signaling during liver regenerationInduction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritisProtective role of STAT3 in NMDA and glutamate-induced neuronal death: negative regulatory effect of SOCS3SOCS2 negatively regulates growth hormone action in vitro and in vivoDysregulation of suppressor of cytokine signaling 3 in keratinocytes causes skin inflammation mediated by interleukin-20 receptor-related cytokinesAberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.The WNT signaling pathway contributes to dectin-1-dependent inhibition of Toll-like receptor-induced inflammatory signatureExchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells.Mechanism of attenuation of leptin signaling under chronic ligand stimulation.Multivariate signaling regulation by SHP2 differentially controls proliferation and therapeutic response in glioma cellsThe T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signalsInterleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology.Signal transduction in the hypothalamic corticotropin-releasing factor system and its clinical implications.IL-6 in inflammation, immunity, and diseaseExpression of suppressor of cytokine signaling-3 (SOCS3) and its role in neuronal death after complete spinal cord injurygp130 at the nexus of inflammation, autoimmunity, and cancer.NANOG amplifies STAT3 activation and they synergistically induce the naive pluripotent program.Loss of expression and function of SOCS3 is an early event in HNSCC: altered subcellular localization as a possible mechanism involved in proliferation, migration and invasionTetraspanin CD37 protects against the development of B cell lymphomaThe paradigm of IL-6: from basic science to medicine
P2860
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P2860
SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@ast
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@en
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@nl
type
label
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@ast
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@en
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@nl
prefLabel
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@ast
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@en
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@nl
P2093
P3181
P356
P1476
SOCS3 exerts its inhibitory fu ...... SHP2 recruitment site of gp130
@en
P2093
M Weissenbach
P C Heinrich
P304
12848-12856
P3181
P356
10.1074/JBC.275.17.12848
P407
P50
P577
2000-04-01T00:00:00Z